{"id":"W2114884360","doi":"10.1093/cid/cis993","title":"Assessment of Cytomegalovirus-Specific Cell-Mediated Immunity for the Prediction of Cytomegalovirus Disease in High-Risk Solid-Organ Transplant Recipients: A Multicenter Cohort Study","year":2012,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":299,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto; University Health Network","funders":"Astellas Pharma; Sanofi; Pfizer","keywords":"Medicine; Cytomegalovirus; Immunology; Immunity; Betaherpesvirinae; Cytomegalovirus infection; Disease; Human cytomegalovirus; Transplantation; Solid organ; Organ transplantation; Cytomegalovirus infections; Cohort; Viral disease; Herpesviridae; Internal medicine; Immune system; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003782213,0.0007538914,0.0005514596,0.0005410141,0.0004840292,0.0007892738,0.0004628528,0.0004397266,0.0008592334],"category_scores_gemma":[0.003093987,0.000394881,0.0006571744,0.0004085041,0.0004047928,0.0005772955,0.0005368533,0.0007014691,0.0002917517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003223378,"about_ca_system_score_gemma":0.0005437997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001001789,"about_ca_topic_score_gemma":0.0008766953,"domain_scores_codex":[0.9989404,0.0004793532,0.00006315372,0.0002377045,0.0001590062,0.0001204338],"domain_scores_gemma":[0.9975623,0.0003954758,0.0007682007,0.0003888651,0.0002475381,0.0006375219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009552792,0.0001752073,0.9972364,0.00000369883,0.00006916948,0.00003767568,0.00004605515,0.00003753399,0.0003621081,0.000006718751,0.00004807331,0.001022131],"study_design_scores_gemma":[0.0002033606,0.003072678,0.9946173,0.000008459172,0.0001102527,0.0005405956,0.0001138677,0.0007282682,0.0003575136,0.00002404885,0.0002114779,0.00001223105],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996283,0.00006648361,0.000114274,0.00001063646,0.000003664373,0.00002087583,0.00007361136,0.000002042121,0.00008009137],"genre_scores_gemma":[0.9994763,0.00003831334,0.0001994743,0.00001176561,0.00001024857,0.00002010714,0.0001828926,0.000001981315,0.00005893047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003782213,"threshold_uncertainty_score":0.02000248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04146719443295607,"score_gpt":0.3727671369125048,"score_spread":0.3312999424795487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}