{"id":"W2114884360","doi":"10.1093/cid/cis993","title":"Assessment of Cytomegalovirus-Specific Cell-Mediated Immunity for the Prediction of Cytomegalovirus Disease in High-Risk Solid-Organ Transplant Recipients: A Multicenter Cohort Study","year":2012,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":299,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto; University Health Network","funders":"Astellas Pharma; Sanofi; Pfizer","keywords":"Medicine; Cytomegalovirus; Immunology; Immunity; Betaherpesvirinae; Cytomegalovirus infection; Disease; Human cytomegalovirus; Transplantation; Solid organ; Organ transplantation; Cytomegalovirus infections; Cohort; Viral disease; Herpesviridae; Internal medicine; Immune system; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002671196,0.0004147111,0.001302873,0.0004470028,0.0002590189,0.00003949879,0.000348891,0.0002178602,0.000291429],"category_scores_gemma":[0.001336607,0.0003021002,0.000681205,0.0007789038,0.0005728608,0.0002936823,0.0001521962,0.0009277393,0.00002752832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003163753,"about_ca_system_score_gemma":0.0004378922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267137,"about_ca_topic_score_gemma":0.0001982447,"domain_scores_codex":[0.9947001,0.0009226088,0.00208898,0.0006132221,0.000914011,0.0007610215],"domain_scores_gemma":[0.993,0.003815048,0.0006665386,0.001166943,0.0004977283,0.000853785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002839809,0.02483758,0.9688081,0.0002468199,0.0007175765,0.000014748,0.0002999785,0.00009725285,0.0005906036,0.00002514217,0.000228284,0.001294138],"study_design_scores_gemma":[0.01240243,0.00202601,0.9811977,0.0001732965,0.001444371,0.000001117367,0.0002207877,0.001422666,0.0001685278,0.00002894938,0.0006794903,0.0002347109],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887928,0.001004194,0.0005368341,0.00005482564,0.0008539618,0.005401448,0.003131245,0.00009651644,0.0001282099],"genre_scores_gemma":[0.9943359,0.003814654,0.00002783592,0.00009350733,0.0004651009,0.0007685735,0.0003666267,0.00007894103,0.00004889322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02281157,"threshold_uncertainty_score":0.9999431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04146719443295607,"score_gpt":0.3727671369125048,"score_spread":0.3312999424795487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}