{"id":"W2114915363","doi":"10.1086/510535","title":"Pathogenesis of <i>Aspergillus fumigatus</i> and the Kinetics of Galactomannan in an In Vitro Model of Early Invasive Pulmonary Aspergillosis: Implications for Antifungal Therapy","year":2007,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Simon Fraser University","keywords":"Aspergillus fumigatus; Galactomannan; Amphotericin B; Aspergillosis; Antifungal drug; Pathogenesis; Microbiology; Biology; Immunology; Antifungal","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717139,0.000568162,0.0003539805,0.0001475092,0.0001298184,0.0005520286,0.0003566067,0.0006020875,0.0003437187],"category_scores_gemma":[0.0002970013,0.0001597359,0.0003806594,0.00008889984,0.0002744426,0.0002095907,0.0001723729,0.0005438741,0.0001553823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001092255,"about_ca_system_score_gemma":0.0003938625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003450407,"about_ca_topic_score_gemma":0.001859121,"domain_scores_codex":[0.9998184,0.00006441807,0.00001404279,0.00002846217,0.00004214785,0.00003248124],"domain_scores_gemma":[0.9997688,0.00009566024,0.00007763797,0.0000174679,0.00002032765,0.00002007036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002649538,0.0002054406,0.003705444,0.0002037502,0.00003864845,0.0003648232,0.00003871965,0.0357194,0.9550053,0.002238662,0.0002137076,0.002001313],"study_design_scores_gemma":[0.0000831401,0.001672871,0.009948157,0.0000526211,0.0001164276,0.001341181,0.00007328584,0.3008218,0.6798796,0.001917498,0.004041925,0.00005149983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9642994,0.003176062,0.02883052,0.0006011762,0.00005322746,0.00008222148,0.0003874244,0.0001162563,0.002453755],"genre_scores_gemma":[0.9932175,0.001223309,0.004754081,0.00005577313,0.000007983484,0.00003754647,0.0001372988,0.000006836762,0.0005597266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003450407,"threshold_uncertainty_score":0.007924914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02082464861612112,"score_gpt":0.2856979314896316,"score_spread":0.2648732828735105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}