{"id":"W2115032517","doi":"10.1211/0022357055434","title":"Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model","year":2005,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Insulin; Chemistry; Small intestine; Chromatography; Sodium Cholate; Permeability (electromagnetism); Sodium; Internal medicine; Biochemistry; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004574062,0.0006052482,0.0003802482,0.000523057,0.0001534332,0.0004134972,0.0003373417,0.0005142574,0.0004810427],"category_scores_gemma":[0.0005464879,0.0001962781,0.000411971,0.0003406714,0.000283328,0.0005314319,0.0002823583,0.0006767071,0.000242778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000471581,"about_ca_system_score_gemma":0.0003100726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001320226,"about_ca_topic_score_gemma":0.0009332707,"domain_scores_codex":[0.9997211,0.00004867963,0.00001925542,0.00006594532,0.0001093179,0.00003571335],"domain_scores_gemma":[0.9996545,0.00008690872,0.0001353221,0.00003917638,0.00006091325,0.0000231616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002791226,0.00003233803,0.0007257848,0.00004032521,0.00001721855,0.00002655588,0.00002290166,0.0007917634,0.9945014,0.0000785685,0.00001797215,0.003466165],"study_design_scores_gemma":[0.00001278218,0.0008522098,0.003965448,0.000005713325,0.00006328904,0.00008031315,0.0000205208,0.01704302,0.9772075,0.00009127539,0.0006457101,0.00001214758],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521484,0.001775519,0.04474408,0.00008392627,0.00002318699,0.00006622591,0.0002588,0.0002319726,0.0006679732],"genre_scores_gemma":[0.9701638,0.002587384,0.02463848,0.00005088539,0.00001154946,0.0001894647,0.0003570471,0.00005112169,0.001950237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320226,"threshold_uncertainty_score":0.003421545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1044959097425121,"score_gpt":0.4353018598058599,"score_spread":0.3308059500633478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}