{"id":"W2115070230","doi":"10.1128/ec.4.1.190-201.2005","title":"Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the<i>Cryptococcus neoformans</i>Cyclic AMP Cascade","year":2005,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Genome Canada; Howard Hughes Medical Institute","keywords":"Cryptococcus neoformans; Melanin; Biology; Gene; Mutant; Virulence; Cell biology; RNA interference; Gene expression; Microbiology; Biochemistry; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102768,0.0003202375,0.0002107018,0.0003350009,0.0002448878,0.0003876777,0.0001306434,0.0002181578,0.0009232027],"category_scores_gemma":[0.0001021932,0.0001401419,0.0002040202,0.0002203602,0.0002539628,0.0001451774,0.000290449,0.0003337856,0.0003617861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006891503,"about_ca_system_score_gemma":0.000426479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002856387,"about_ca_topic_score_gemma":0.002466117,"domain_scores_codex":[0.9997851,0.00001953609,0.000007543466,0.00007420905,0.00004532607,0.00006832006],"domain_scores_gemma":[0.9998647,0.00001405011,0.00003296848,0.0000081047,0.00003436333,0.00004581019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007530637,0.00001598162,0.000945591,0.00002011713,0.000001816657,0.00006121722,0.00002132167,0.00008094418,0.9971872,0.0001061871,0.00008209226,0.001402231],"study_design_scores_gemma":[0.00003940049,0.0003257815,0.1378336,0.00003922746,0.00003589879,0.0007778546,0.0002517243,0.006774308,0.8469716,0.0004615621,0.006464913,0.00002398434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922213,0.0008891278,0.002787469,0.0001790114,0.00001572199,0.00004235871,0.0008859584,0.0001287112,0.002850201],"genre_scores_gemma":[0.9930856,0.0003659985,0.002362359,0.0001059579,0.00000975511,0.00003475402,0.001058088,0.00001438209,0.002963036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002856387,"threshold_uncertainty_score":0.005679488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261468269670968,"score_gpt":0.2275104733634237,"score_spread":0.214895790666714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}