{"id":"W2115070230","doi":"10.1128/ec.4.1.190-201.2005","title":"Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the<i>Cryptococcus neoformans</i>Cyclic AMP Cascade","year":2005,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Genome Canada; Howard Hughes Medical Institute","keywords":"Cryptococcus neoformans; Melanin; Biology; Gene; Mutant; Virulence; Cell biology; RNA interference; Gene expression; Microbiology; Biochemistry; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429872,0.0001458125,0.0002496609,0.0000192729,0.0001766609,0.00001045018,0.000055057,0.00006325212,0.0002028921],"category_scores_gemma":[0.00001707884,0.0001016412,0.00009223315,0.0001233072,0.0001278713,0.00005651062,0.00002742507,0.0001563955,0.00003969777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004240493,"about_ca_system_score_gemma":0.00002645213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002841247,"about_ca_topic_score_gemma":0.0002613551,"domain_scores_codex":[0.9991069,0.00002902958,0.0002625902,0.0001677991,0.0001807529,0.0002528781],"domain_scores_gemma":[0.9995415,0.00009427845,0.00006711471,0.0001719707,0.00004555325,0.00007964943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004036023,0.001226359,0.4846287,0.0004084254,0.000497707,0.0000151757,0.003504131,0.002356942,0.2369824,0.000684727,0.2529662,0.01632554],"study_design_scores_gemma":[0.004123729,0.0004244324,0.6782145,0.00008147412,0.0003163422,0.0001270136,0.0003803036,0.002657257,0.02761745,0.00009885203,0.285623,0.0003355902],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977731,0.01231582,0.0004386862,0.001586728,0.00020139,0.000415303,0.00004399748,0.00003600864,0.007231102],"genre_scores_gemma":[0.9923931,0.001117895,0.0007931926,0.0004787094,0.0003237022,0.00002578913,0.00002809637,0.00001645276,0.004823108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.209365,"threshold_uncertainty_score":0.414481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261468269670968,"score_gpt":0.2275104733634237,"score_spread":0.214895790666714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}