{"id":"W2115073288","doi":"10.1186/1742-4690-10-102","title":"HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity","year":2013,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Rijksinstituut voor Volksgezondheid en Milieu; Norwegian Biodiversity Information Centre; York University; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institutes of Health; International AIDS Vaccine Initiative; Universiteit van Amsterdam; Stichting Sanquin Bloedvoorziening","keywords":"Glycoprotein; Antibody; Epitope; Seroconversion; Virology; Glycosylation; Biology; Neutralizing antibody; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002896644,0.0001855361,0.0001552645,0.000353256,0.0001846958,0.0003325377,0.0001652431,0.0003365364,0.001146021],"category_scores_gemma":[0.0007573089,0.00009849308,0.0001631582,0.0002303598,0.0001661211,0.0002064071,0.0002199502,0.0003891542,0.0001632602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001893148,"about_ca_system_score_gemma":0.00009936238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002870116,"about_ca_topic_score_gemma":0.0002415536,"domain_scores_codex":[0.9998449,0.00002275846,0.00001503794,0.00004263462,0.00003199205,0.00004272669],"domain_scores_gemma":[0.9993855,0.0001087635,0.0002937497,0.00003945352,0.00008301694,0.0000895043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007767005,0.0001374365,0.8391944,0.00005887981,0.00006711133,0.001250559,0.0003229305,0.0004252621,0.1458807,0.0002059347,0.0001240982,0.01155606],"study_design_scores_gemma":[0.000007549434,0.0005966985,0.9804189,0.000008926298,0.0000427798,0.00528927,0.0001318294,0.0003923431,0.01247892,0.00009254168,0.0005332116,0.000007119048],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993094,0.0001320214,0.0001376302,0.000006719485,0.000001503712,0.000006319401,0.00004906392,0.000003158801,0.000354143],"genre_scores_gemma":[0.9995981,0.00003540586,0.0001380535,0.000009866241,0.000003245886,0.00000402381,0.0001092306,0.000001322403,0.0001008005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001146021,"threshold_uncertainty_score":0.00383383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01681518094408233,"score_gpt":0.2592725040072565,"score_spread":0.2424573230631742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}