{"id":"W2115086893","doi":"10.1093/jac/dkt137","title":"Nystatin nanosizing enhances in vitro and in vivo antifungal activity against Candida albicans","year":2013,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Nystatin; Candida albicans; In vivo; In vitro; Pharmacology; Microbiology; Corpus albicans; Pharmacokinetics; Chemistry; Medicine; Biology; Antifungal; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000309354,0.0001642477,0.0002995387,0.0001834935,0.00004176975,0.00006546949,0.0001941531,0.0001324071,0.00004550243],"category_scores_gemma":[0.00003689764,0.0001438547,0.00007727755,0.0001654526,0.0001051443,0.0000297546,0.00004226626,0.0002654465,9.381042e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004277995,"about_ca_system_score_gemma":0.0001726657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004626376,"about_ca_topic_score_gemma":0.0003165741,"domain_scores_codex":[0.9988659,0.00009132417,0.0003423912,0.0002176306,0.0001456878,0.0003370904],"domain_scores_gemma":[0.9994836,0.000020783,0.0001818332,0.000127982,0.00009362105,0.00009222347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007276105,0.0001291967,0.003586479,0.0000241934,0.00002646945,0.00002088184,0.0001082007,0.00001509451,0.9778699,3.403102e-7,0.0009864927,0.0165051],"study_design_scores_gemma":[0.001920626,0.0001671526,0.006940333,0.00007035756,0.000002035063,0.00004644077,0.00004444929,0.00006567863,0.9882004,0.000009521448,0.002373141,0.0001599226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998138,0.0002300244,0.000204088,0.0009034967,0.00007609981,0.0002220115,0.0000131419,0.00000194326,0.0002111903],"genre_scores_gemma":[0.9960781,0.002092303,0.001014928,0.0005122661,0.0001277424,0.000005108437,0.000002830111,0.00002074732,0.0001459631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01634517,"threshold_uncertainty_score":0.5866223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006453475121229559,"score_gpt":0.2497911352499208,"score_spread":0.2433376601286913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}