{"id":"W2115095020","doi":"10.1093/hmg/ddm281","title":"Coordinated diurnal regulation of genes from the Dlk1–Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes","year":2007,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Douglas Mental Health University Institute; McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; McGill University","keywords":"Congenic; Enhancer; Biology; Genomic imprinting; Gene; Genetics; Imprinting (psychology); Regulation of gene expression; Genome; Regulator; Chromosome; Regulatory sequence; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009171579,0.0002259599,0.0001574489,0.0001998884,0.0001010442,0.0002151506,0.0001933405,0.0001356919,0.0007636786],"category_scores_gemma":[0.00009283034,0.000115989,0.0001759323,0.0001049009,0.0002317962,0.0001474505,0.0002318606,0.0003260311,0.0001382176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002645706,"about_ca_system_score_gemma":0.0001259083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005998767,"about_ca_topic_score_gemma":0.001565108,"domain_scores_codex":[0.9999045,0.000008637484,0.00000632276,0.00004007564,0.00001720387,0.0000233293],"domain_scores_gemma":[0.9997931,0.0000256433,0.00008221484,0.00002172497,0.00001325983,0.00006405879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004821344,0.000003309728,0.0006414924,0.00000666196,0.000001025006,0.00001574086,0.000008735077,0.00001176113,0.9988726,0.00002611316,0.00000401283,0.0003603509],"study_design_scores_gemma":[0.00002093527,0.0001191324,0.2106711,0.000009133688,0.0000200805,0.0003331703,0.00009676901,0.0008907309,0.7864761,0.0001333987,0.001217418,0.00001206809],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965917,0.0005751877,0.002024736,0.00004453752,0.000009136184,0.000005879707,0.000283857,0.00004136494,0.0004236923],"genre_scores_gemma":[0.99544,0.0002865829,0.001976725,0.00005235513,0.000005983881,0.00001768791,0.0005321858,0.00003352982,0.001654948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007636786,"threshold_uncertainty_score":0.002554774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01407394754241824,"score_gpt":0.2748342011835551,"score_spread":0.2607602536411369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}