{"id":"W2115249576","doi":"10.1021/bp000066y","title":"Bone Affinity of a Bisphosphonate-Conjugated Protein in Vivo","year":2000,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Bone health and treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Bisphosphonate; Conjugated system; In vivo; Chemistry; Medicine; Internal medicine; Biology; Osteoporosis; Biotechnology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002718338,0.0004254944,0.0002473324,0.0002882303,0.0001606498,0.0002224083,0.0001941474,0.0003777641,0.001005716],"category_scores_gemma":[0.0001824491,0.0002495521,0.0001447742,0.0001761717,0.0002316469,0.0002169139,0.0001240283,0.0004338306,0.0002962733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003185305,"about_ca_system_score_gemma":0.0002523303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00145759,"about_ca_topic_score_gemma":0.001714443,"domain_scores_codex":[0.9998348,0.00003917661,0.000006615574,0.00003841113,0.00004004133,0.00004083598],"domain_scores_gemma":[0.9998265,0.00006068239,0.00004413673,0.00001249562,0.00002323488,0.00003301466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000145535,0.00002416867,0.0000672871,0.00001591891,0.000002763215,0.00001260108,0.00001350452,0.00003151055,0.9991484,0.00003423199,0.000008639401,0.00049547],"study_design_scores_gemma":[0.00001303249,0.0007702069,0.001361823,0.000002751646,0.00001395571,0.00007968977,0.00001302837,0.0005260197,0.9966688,0.00001936042,0.000528044,0.000003395711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963486,0.0008314005,0.002135273,0.00003884455,0.00001176806,0.00001100321,0.00005403534,0.00002817393,0.0005407589],"genre_scores_gemma":[0.9936873,0.0007319778,0.002379158,0.00002921212,0.000008946417,0.00001740724,0.0001974139,0.00002109288,0.002927444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145759,"threshold_uncertainty_score":0.003364444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246945717922786,"score_gpt":0.2743145460688829,"score_spread":0.2618450888896551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}