{"id":"W2115317196","doi":"10.1016/j.molimm.2007.04.003","title":"Alpha2beta1 integrin signaling augments T cell receptor-dependent production of interferon-gamma in human T cells","year":2007,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research","keywords":"Integrin; T-cell receptor; Cell biology; PI3K/AKT/mTOR pathway; MAPK/ERK pathway; T cell; Protein kinase B; Signal transduction; Interferon gamma; Biology; Chemistry; Receptor; Cytokine; Immunology; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009885496,0.0002309205,0.000456024,0.0007352282,0.00004175066,0.000009159472,0.0002748778,0.000253873,0.0004290756],"category_scores_gemma":[0.0001107929,0.0002323187,0.0001347388,0.0004132632,0.0001946078,0.00004541488,0.0002390413,0.0007288015,0.0001208147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003329391,"about_ca_system_score_gemma":0.00008596116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001965742,"about_ca_topic_score_gemma":0.00002961583,"domain_scores_codex":[0.9975017,0.0002219483,0.0007333315,0.0005263675,0.0004402935,0.0005763895],"domain_scores_gemma":[0.9988728,0.00004845469,0.0001760897,0.0006058229,0.0002017841,0.00009511656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006912174,0.0005765816,0.001205347,0.000106359,0.00008178277,0.0002923608,0.0002836947,0.00005379586,0.9931189,0.00004902641,0.00009206708,0.003448852],"study_design_scores_gemma":[0.00166941,0.001028661,0.001362154,0.0001311833,0.00002627213,0.00003739455,0.000403002,0.00001174797,0.9943862,0.00004600658,0.0007342127,0.0001637452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939358,0.0008779728,0.001859735,0.000180799,0.0004113402,0.000686506,0.000001256337,0.00003714453,0.002009493],"genre_scores_gemma":[0.9967212,0.0000654203,0.0008870474,0.00006811654,0.00003906262,0.00001847596,0.00003833528,0.00005136215,0.002110987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003285107,"threshold_uncertainty_score":0.9473683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01528242785249318,"score_gpt":0.2958713651207398,"score_spread":0.2805889372682466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}