{"id":"W2115341402","doi":"10.1111/j.1749-6632.2002.tb02108.x","title":"Oxidative Stress and Programmed Cell Death in Diabetic Neuropathy","year":2002,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":361,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; NIH Clinical Center; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; University of Calgary; National Institute of Neurological Disorders and Stroke; Geriatric Research Education and Clinical Center; University of Michigan","keywords":"Oxidative stress; Depolarization; Dorsal root ganglion; Programmed cell death; Mitochondrion; Reactive oxygen species; Cell biology; Apoptosis; Streptozotocin; Endocrinology; Internal medicine; Medicine; Chemistry; Pharmacology; Diabetes mellitus; Biology; Neuroscience; Biochemistry; Sensory system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002437011,0.000317245,0.0001940528,0.000839342,0.0001816334,0.0003950698,0.0002114759,0.0004316488,0.0006716282],"category_scores_gemma":[0.0001513145,0.00009166743,0.0001238262,0.0004393009,0.0003389704,0.0003520791,0.0003545817,0.0004918344,0.00009739056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003481098,"about_ca_system_score_gemma":0.0001531633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004497236,"about_ca_topic_score_gemma":0.0005482399,"domain_scores_codex":[0.9999083,0.00002468732,0.00001367776,0.00001663585,0.0000232558,0.00001342984],"domain_scores_gemma":[0.9998491,0.00002427787,0.00007300805,0.000004695634,0.00002152858,0.00002728421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.005431562,0.001520554,0.06416152,0.009966998,0.0005241846,0.01359094,0.00132159,0.003610798,0.2617172,0.0335133,0.006637392,0.598004],"study_design_scores_gemma":[0.0004701127,0.007526353,0.6274439,0.003027076,0.0005151978,0.03833951,0.001731058,0.005704311,0.08074651,0.08109207,0.1531921,0.0002119368],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2637576,0.7271153,0.002062793,0.001055254,0.0003422025,0.00005657251,0.0001288691,0.00003211266,0.005449405],"genre_scores_gemma":[0.7110947,0.2811621,0.001735872,0.000660031,0.0004860761,0.00006560338,0.0001969659,0.000003890653,0.004594864],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.000839342,"threshold_uncertainty_score":0.002525687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09859008576697828,"score_gpt":0.3253613059885204,"score_spread":0.2267712202215421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}