{"id":"W2115369621","doi":"10.1158/1055-9965.epi-08-1101","title":"HER-2/neu Overexpression as a Predictor for the Transition from <i>In situ</i> to Invasive Breast Cancer","year":2009,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; National Institutes of Health","keywords":"Ductal carcinoma; Progesterone receptor; Breast cancer; Estrogen receptor; Oncology; Pathology; Immunohistochemistry; Medicine; Internal medicine; Univariate analysis; Cancer; Biology; Multivariate analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001821285,0.0003107274,0.0006802579,0.0001910976,0.0001626656,0.00001424346,0.0002897556,0.0003797831,0.0006642686],"category_scores_gemma":[0.0007137045,0.0002333879,0.0003165051,0.000402297,0.0001603468,0.0001617786,0.00004438401,0.000392442,0.00002799465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009167632,"about_ca_system_score_gemma":0.0007115186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003707161,"about_ca_topic_score_gemma":0.002494394,"domain_scores_codex":[0.9966308,0.0006956102,0.0007703328,0.0008574136,0.0002911547,0.0007546236],"domain_scores_gemma":[0.9972116,0.001496381,0.0002350888,0.0005422038,0.0001910147,0.0003236567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01897183,0.0006389376,0.1070529,0.000403681,0.001033446,0.00003331929,0.001671594,0.0008128058,0.3237166,0.0002600078,0.2185477,0.3268572],"study_design_scores_gemma":[0.006142048,0.001262156,0.9430333,0.00565189,0.000432038,0.00003615327,0.0003534039,0.001314778,0.01140233,0.01685793,0.01303816,0.000475835],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.762265,0.01754818,0.009128156,0.2014642,0.001405404,0.006854177,0.0007566132,0.00015166,0.0004265309],"genre_scores_gemma":[0.9738855,0.004183535,0.001677133,0.01511615,0.001323135,0.002945218,0.0002755319,0.00005178537,0.0005419867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8359804,"threshold_uncertainty_score":0.9517283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06706633794037227,"score_gpt":0.4246865636325911,"score_spread":0.3576202256922188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}