{"id":"W2115370961","doi":"10.1128/mcb.01461-08","title":"High-Affinity Transporters for NAD <sup>+</sup> Precursors in <i>Candida glabrata</i> Are Regulated by Hst1 and Induced in Response to Niacin Limitation","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Niacin; Candida glabrata; NAD+ kinase; Biology; Transporter; Mutant; Auxotrophy; Gene; Membrane transport protein; Biochemistry; Microbiology; Candida albicans; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009851291,0.0004817239,0.0004960669,0.0003056504,0.0003049012,0.0006451452,0.0001910788,0.0003215147,0.0009193841],"category_scores_gemma":[0.0001703418,0.0001978079,0.0005974455,0.0004209216,0.0002555631,0.000182709,0.000418094,0.000821979,0.0005015437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004623644,"about_ca_system_score_gemma":0.0002633443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003333005,"about_ca_topic_score_gemma":0.003118392,"domain_scores_codex":[0.9997345,0.00002174434,0.00002559575,0.00006981906,0.00006382728,0.00008443903],"domain_scores_gemma":[0.9997725,0.00002937689,0.00006723134,0.00002956105,0.0000497166,0.00005161988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001088019,0.00001570433,0.0003386114,0.00001960476,0.000002362039,0.00003161447,0.00001935171,0.00002314036,0.9990076,0.0000205351,0.00003383922,0.0003787688],"study_design_scores_gemma":[0.00001818142,0.0002064537,0.07714578,0.00001382977,0.00002165076,0.0003238648,0.0001665318,0.001219285,0.9187593,0.00006284878,0.002042516,0.00001975457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937611,0.001117435,0.00116981,0.0001827349,0.00003249574,0.0000286755,0.002633758,0.0001249817,0.0009490481],"genre_scores_gemma":[0.9839807,0.0006600538,0.002603273,0.0002012751,0.0000195278,0.00007251681,0.007226997,0.00006816367,0.005167471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003333005,"threshold_uncertainty_score":0.006627202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009063082821750668,"score_gpt":0.2470194606940108,"score_spread":0.2379563778722601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}