{"id":"W2115434419","doi":"10.3389/fphar.2013.00088","title":"Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles","year":2013,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Comisión Nacional de Investigación Científica y Tecnológica; Vlaamse regering; Heart and Stroke Foundation of Canada","keywords":"Connexin; Pannexin; Connexon; Pharmacology; Gap junction; Neuroscience; Ion channel; Medicine; Chemistry; Biology; Cell biology; Internal medicine; Receptor; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390853,0.0002283004,0.0004117617,0.0006899481,0.000371813,0.0006110953,0.0003281448,0.0007779122,0.0005406229],"category_scores_gemma":[0.000214832,0.0001236492,0.0001979119,0.0006893027,0.0007487158,0.001525469,0.000387733,0.0009292401,0.0001350293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003995028,"about_ca_system_score_gemma":0.0003674018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007073936,"about_ca_topic_score_gemma":0.0007432912,"domain_scores_codex":[0.9998265,0.00004232005,0.00002494198,0.00004223208,0.00003720206,0.0000268635],"domain_scores_gemma":[0.9998983,0.00002247158,0.00002938927,0.000005606564,0.00002432474,0.00001978316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005387986,0.0001351555,0.005164607,0.006022846,0.0001362791,0.005669937,0.001863498,0.001116039,0.6340849,0.1106566,0.005498687,0.2291127],"study_design_scores_gemma":[0.00006985699,0.000995926,0.09852155,0.001507525,0.000324815,0.03248489,0.002175979,0.005658865,0.2217487,0.1038995,0.5323724,0.0002399366],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08698124,0.8947405,0.007738367,0.002734168,0.0005241302,0.00002648787,0.0001073261,0.00006089572,0.007086955],"genre_scores_gemma":[0.4967468,0.4894647,0.005821071,0.0008150216,0.001120477,0.00006158152,0.0001794391,0.00001909734,0.00577184],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0007779122,"threshold_uncertainty_score":0.002898574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006884801483554529,"score_gpt":0.2326768793684527,"score_spread":0.2257920778848982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}