{"id":"W2115447066","doi":"10.1093/nar/gkt1104","title":"Prospective identification of parasitic sequences in phage display screens","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Institut National de la Recherche Agronomique","keywords":"Biology; Phage display; Selection (genetic algorithm); Genomic library; Genetics; Computational biology; Population; Function (biology); DNA sequencing; Negative selection; Identification (biology); Ion semiconductor sequencing; Genome; DNA; Gene; Base sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001283597,0.0001190459,0.0002909349,0.0004639627,0.0001224204,0.00004854427,0.0002747399,0.0001032191,0.001203006],"category_scores_gemma":[0.0004729735,0.00009074896,0.00007693824,0.0009173503,0.0007004364,0.0002196931,0.00009723642,0.0006378657,0.0009569364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001424516,"about_ca_system_score_gemma":0.0001880323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002236592,"about_ca_topic_score_gemma":0.00006151494,"domain_scores_codex":[0.9971198,0.0002308554,0.0004292323,0.000361517,0.00127366,0.0005848714],"domain_scores_gemma":[0.998444,0.000295038,0.00005206516,0.0003498874,0.0006599854,0.000199056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002925997,0.0004340899,0.5966237,0.0002935592,0.00005028556,0.00007784657,0.000807248,0.000003025417,0.3866033,0.004738074,0.001454402,0.008621902],"study_design_scores_gemma":[0.0006235376,0.0004511934,0.9432589,0.0001346936,0.000006076204,0.00002667291,0.0007318375,0.001583714,0.04970581,0.002939821,0.000445131,0.00009254929],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826116,0.000280319,0.00002049144,0.002286979,0.00003640918,0.001106857,0.00001733446,0.0000180664,0.01362195],"genre_scores_gemma":[0.9897483,0.0001767282,0.0002652858,0.0000361756,0.0000927373,0.0001587355,0.00002057671,0.00001829685,0.009483155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3466353,"threshold_uncertainty_score":0.9998209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05408427368687006,"score_gpt":0.3953533811962659,"score_spread":0.3412691075093958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}