{"id":"W2115449902","doi":"10.1093/nar/gki934","title":"Structure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase","year":2005,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Biochemistry; Intron; Phosphodiester bond; RNA; Amino acid; Saccharomyces cerevisiae; RNA splicing; Glycogen debranching enzyme; Alanine; Molecular biology; Yeast; Enzyme; Gene; Glycogen synthase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008580504,0.0003600015,0.0001639769,0.0001203598,0.00007461946,0.0001319205,0.0002134418,0.0001536831,0.0005019074],"category_scores_gemma":[0.0001224822,0.00009527771,0.0002167461,0.0001584371,0.00009525228,0.00006963955,0.00008182283,0.0002287665,0.0002608128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002690571,"about_ca_system_score_gemma":0.0001427085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001240418,"about_ca_topic_score_gemma":0.0009140426,"domain_scores_codex":[0.9999588,0.000007579572,0.000003933176,0.00001038937,0.00001294522,0.000006359934],"domain_scores_gemma":[0.9999238,0.00001564933,0.00002402729,0.00000555613,0.00001221496,0.0000187405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001289876,0.00003586786,0.0008343629,0.00003515738,0.000007080369,0.00008799927,0.00001646169,0.000386623,0.9968183,0.00006956397,0.00002204293,0.001557518],"study_design_scores_gemma":[0.0000226126,0.0002741196,0.01362973,0.000005123026,0.00002525832,0.0004687758,0.00003582199,0.004535278,0.979211,0.00004133787,0.00174475,0.0000061814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978517,0.0004833032,0.0009887515,0.0000317468,0.000004918347,0.000008642806,0.0003249065,0.00002382567,0.0002822689],"genre_scores_gemma":[0.9947195,0.0005388639,0.002558128,0.00001919142,0.000002536244,0.000008449842,0.001410838,0.00001519448,0.0007272947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240418,"threshold_uncertainty_score":0.00246644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956106644999338,"score_gpt":0.3153577279325543,"score_spread":0.2957966614825609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}