{"id":"W2115543229","doi":"10.1093/hmg/11.20.2517","title":"Pharmacogenomics in schizophrenia: the quest for individualized therapy","year":2002,"lang":"en","type":"review","venue":"Human Molecular Genetics","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Pharmacogenomics; Pharmacogenetics; Biology; Candidate gene; Schizophrenia (object-oriented programming); Clozapine; Neurocognitive; Bioinformatics; Genetics; Gene; Neuroscience; Psychiatry; Genotype; Medicine; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007313973,0.001211629,0.003810591,0.002153791,0.0007003516,0.00376107,0.001463978,0.002767558,0.002184543],"category_scores_gemma":[0.009051342,0.0005381256,0.001304177,0.001188661,0.004230746,0.003573678,0.003239027,0.01000849,0.0008389038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003117931,"about_ca_system_score_gemma":0.004538347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002233328,"about_ca_topic_score_gemma":0.00312285,"domain_scores_codex":[0.9974641,0.001472437,0.0002266569,0.000280097,0.0004449914,0.0001118582],"domain_scores_gemma":[0.9943064,0.003872052,0.0003041236,0.0005813123,0.000629307,0.0003068801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004124879,0.0003213479,0.008131103,0.004550567,0.001543365,0.001408252,0.0007232108,0.004468016,0.003703097,0.1738009,0.05266989,0.7482678],"study_design_scores_gemma":[0.0001651088,0.0003679457,0.009102971,0.005519887,0.0008088066,0.001445224,0.0009038555,0.005125009,0.001157842,0.7081983,0.2670215,0.0001835935],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004694655,0.6378873,0.03326678,0.3122976,0.002467144,0.00008226299,0.0003764301,0.0004375615,0.008490381],"genre_scores_gemma":[0.06867556,0.8381571,0.0377993,0.0423896,0.009312353,0.0002722045,0.0003749496,0.0001286717,0.002890242],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007313973,"threshold_uncertainty_score":0.03868043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1262608731518765,"score_gpt":0.4158637969052974,"score_spread":0.2896029237534209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}