{"id":"W2115555388","doi":"10.1261/rna.030346.111","title":"The 5′ UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed −1 ribosomal frameshift that generates HIV-1 enzymes","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Biology; Translational frameshift; Frameshift mutation; Human immunodeficiency virus (HIV); Messenger RNA; Ribosomal RNA; Ribosomal protein; Untranslated region; Ribosome; Enzyme; Computational biology; Virology; Genetics; Translation (biology); Molecular biology; RNA; Gene; Biochemistry; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007276969,0.0002051126,0.0002421136,0.00002882494,0.0006677664,0.00006190646,0.0003605055,0.0001294161,0.00009743636],"category_scores_gemma":[0.00008346469,0.00008028097,0.0001172222,0.00007900722,0.001310116,0.00009939996,0.0001785793,0.0003811844,0.0003596879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002024515,"about_ca_system_score_gemma":0.00004528753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001015043,"about_ca_topic_score_gemma":0.00003785656,"domain_scores_codex":[0.9981157,0.0006850252,0.000216397,0.0001911552,0.00009325951,0.0006984945],"domain_scores_gemma":[0.9989419,0.0004050296,0.0001243155,0.0004328531,0.00004656876,0.0000493431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008115621,0.001891201,0.05999214,0.000166174,0.006025224,0.00003303889,0.01489158,0.00001825903,0.4163482,0.1322553,0.02854679,0.3317165],"study_design_scores_gemma":[0.01000329,0.0009387464,0.03225226,0.00008635092,0.0002868724,0.0001668645,0.002279196,0.0001069649,0.6996268,0.002339207,0.2513858,0.0005276237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9530414,0.03916277,0.00004086,0.005576804,0.0001515439,0.001324378,0.0001005161,0.00003602979,0.0005656421],"genre_scores_gemma":[0.9952559,0.0004646518,0.00009238847,0.00006131383,0.00008830806,0.0003579548,0.00007211132,0.00001699523,0.003590397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3311889,"threshold_uncertainty_score":0.5135986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306308111650398,"score_gpt":0.2388868068618586,"score_spread":0.2258237257453547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}