{"id":"W2115618910","doi":"10.1128/mcb.25.9.3452-3460.2005","title":"Sequence-Specific DNA Binding by the αNAC Coactivator Is Required for Potentiation of c-Jun-Dependent Transcription of the Osteocalcin Gene","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"McGill University","keywords":"Osteocalcin; Coactivator; Biology; Chromatin immunoprecipitation; Molecular biology; Promoter; Transcription factor; Transcription (linguistics); Response element; Gene; Gene expression; Cell biology; Genetics; Biochemistry; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850945,0.0001374421,0.0001739017,0.00002638957,0.00009355229,0.000008594098,0.0001863858,0.0001615638,0.00001317272],"category_scores_gemma":[0.00002125924,0.0000906483,0.0001763093,0.00007191826,0.0001955447,0.000005216793,0.00005154693,0.00004721174,7.623152e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007005509,"about_ca_system_score_gemma":0.000034918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001982806,"about_ca_topic_score_gemma":0.000002847053,"domain_scores_codex":[0.9990445,0.0001357998,0.0002664666,0.0002814838,0.00009246385,0.000179337],"domain_scores_gemma":[0.9993995,0.0000108229,0.0001582146,0.0003227247,0.00006846755,0.00004023235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001068433,0.00005312491,0.0001459171,0.00001769557,0.0000530495,2.063908e-7,0.00004778311,0.000007206043,0.9947807,0.0003780054,0.0004384119,0.003971085],"study_design_scores_gemma":[0.0006654661,0.0001225836,0.0001329819,0.000005665129,0.000070168,0.000004452516,0.00006691254,0.00003278292,0.9832276,0.0001696033,0.01539761,0.0001042062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708433,0.01046119,0.0173241,0.0005210689,0.0001215073,0.0003540817,0.0003281097,0.000003932227,0.00004275747],"genre_scores_gemma":[0.9985753,0.0003728474,0.0001733192,0.0003023279,0.00006968759,0.00002769162,0.0003063751,0.00001478712,0.0001576998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02773201,"threshold_uncertainty_score":0.369653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388966996557385,"score_gpt":0.2329293779649215,"score_spread":0.2190397079993476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}