{"id":"W2115618910","doi":"10.1128/mcb.25.9.3452-3460.2005","title":"Sequence-Specific DNA Binding by the αNAC Coactivator Is Required for Potentiation of c-Jun-Dependent Transcription of the Osteocalcin Gene","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"McGill University","keywords":"Osteocalcin; Coactivator; Biology; Chromatin immunoprecipitation; Molecular biology; Promoter; Transcription factor; Transcription (linguistics); Response element; Gene; Gene expression; Cell biology; Genetics; Biochemistry; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181721,0.0002853095,0.0002303931,0.0001487582,0.0001411923,0.0002553407,0.0001785283,0.0001289176,0.001318841],"category_scores_gemma":[0.0001892327,0.000155127,0.0002911304,0.0001204217,0.000228238,0.0001140645,0.0002784862,0.0004932666,0.0005746599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003154117,"about_ca_system_score_gemma":0.000212357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006642264,"about_ca_topic_score_gemma":0.001277687,"domain_scores_codex":[0.9998222,0.00002271073,0.00001408109,0.00004089042,0.00005476191,0.00004548689],"domain_scores_gemma":[0.999797,0.00002933122,0.00005217374,0.00002572112,0.00003025439,0.00006541651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004072889,0.000008808787,0.00009026161,0.00000985345,0.000001512532,0.00001597196,0.000005177288,0.00001080617,0.9994606,0.00001876169,0.000005959823,0.0003314792],"study_design_scores_gemma":[0.00001911148,0.0001832056,0.01317734,0.000009301038,0.00001178604,0.000296645,0.00004144929,0.001265023,0.982195,0.00005556168,0.002740562,0.000004993432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943692,0.001194105,0.002632248,0.00006176374,0.00003039372,0.00001917675,0.0001683063,0.00005856961,0.001466208],"genre_scores_gemma":[0.9941295,0.000435141,0.002123974,0.00004734173,0.00001047439,0.00002689196,0.0006823298,0.00002525651,0.002519208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001318841,"threshold_uncertainty_score":0.004411995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388966996557385,"score_gpt":0.2329293779649215,"score_spread":0.2190397079993476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}