{"id":"W2115633795","doi":"10.1677/joe-09-0117","title":"Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin","year":2009,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of New Brunswick; Canada Research Chairs","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Streptozotocin; Diabetes mellitus; Beta cell; Glucagon; Reactive oxygen species; Insulin; Islet; Alpha cell; Secretion; Chemistry; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001889887,0.00008539955,0.0003607509,0.0003147084,0.00002263879,0.000005948553,0.00004092872,0.00005139378,0.0000343395],"category_scores_gemma":[0.0005627539,0.00006763607,0.00005375347,0.0001666888,0.00005214358,0.0002152154,0.00001279695,0.0001652091,0.000001397742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001042252,"about_ca_system_score_gemma":0.00004624095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001948594,"about_ca_topic_score_gemma":0.0000147136,"domain_scores_codex":[0.9990497,0.00004854928,0.0004909841,0.00009996512,0.0001448912,0.0001658882],"domain_scores_gemma":[0.9992375,0.00008596612,0.0003125252,0.00009952384,0.0001950308,0.00006944971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005198575,0.00009715411,0.04815096,0.00004435533,0.00003153228,0.00001483027,0.0003782274,0.00005921954,0.9447785,0.0001168667,0.00004803872,0.00576043],"study_design_scores_gemma":[0.0009580291,0.001245912,0.4759009,0.0001344102,0.00002949832,0.0001060805,0.0007643791,0.00003991627,0.5197353,0.0009151882,0.0001272144,0.00004306853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978767,0.00019995,0.0000451938,0.001154019,0.00005776182,0.0002988279,0.000001214035,0.000007026652,0.0003593012],"genre_scores_gemma":[0.9989293,0.00005665774,0.0007586093,0.0001159724,0.00006686541,0.000003748642,0.000001525665,0.000003061242,0.00006432664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.42775,"threshold_uncertainty_score":0.2758119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03187237797164273,"score_gpt":0.3021243500491358,"score_spread":0.2702519720774931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}