{"id":"W2115640225","doi":"10.1016/j.exphem.2010.01.003","title":"Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia","year":2010,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Deutsche Forschungsgemeinschaft; Terry Fox Foundation; Cancer Research Society","keywords":"Haematopoiesis; Leukemia; Myeloid leukemia; Bone marrow; Biology; Myeloid; Cancer research; Phenotype; Lineage (genetic); Knockout mouse; Transplantation; Cell biology; Immunology; Stem cell; Receptor; Genetics; Medicine; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001688135,0.0002116746,0.0001660863,0.0002451128,0.0002498199,0.0005943995,0.0002201617,0.0002293505,0.003234647],"category_scores_gemma":[0.0002104701,0.0001667415,0.0001030261,0.0001347518,0.000220214,0.0004564934,0.0003981879,0.0008024877,0.0005425872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005030943,"about_ca_system_score_gemma":0.0001854175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004891299,"about_ca_topic_score_gemma":0.001338208,"domain_scores_codex":[0.9998015,0.00003929586,0.00001351955,0.00003160907,0.00003788439,0.00007623406],"domain_scores_gemma":[0.9998747,0.00002843268,0.00003321601,0.00001474674,0.00001323451,0.00003561091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008254891,0.00004531876,0.001748119,0.00005325508,0.000004484791,0.0001072347,0.00006141677,0.000145216,0.9904771,0.003193689,0.0001869332,0.003151697],"study_design_scores_gemma":[0.00005367603,0.0002729752,0.03134314,0.0000213007,0.00002366048,0.0004088287,0.0002579535,0.002287319,0.9538667,0.0005283396,0.01092898,0.000007154749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936122,0.001180463,0.001503529,0.0001262974,0.00002400239,0.00001517558,0.0003474226,0.00003378197,0.003157036],"genre_scores_gemma":[0.995831,0.0003904193,0.0005917167,0.00004216878,0.00001336391,0.00001390722,0.0004043052,0.00001610781,0.002696996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003234647,"threshold_uncertainty_score":0.01082098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02177275617014895,"score_gpt":0.3309468304403738,"score_spread":0.3091740742702248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}