{"id":"W2115646982","doi":"10.1002/glia.21093","title":"The role of TLR2 in nerve injury‐induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response","year":2010,"lang":"en","type":"article","venue":"Glia","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval","funders":"Canadian Institutes of Health Research; McGill University","keywords":"TLR2; Microglia; Nerve injury; Peripheral nerve injury; Proinflammatory cytokine; Inflammation; Neuropathic pain; Central nervous system; Hyperalgesia; Tumor necrosis factor alpha; Receptor; Medicine; Biology; Immunology; Neuroscience; TLR4; Internal medicine; Sciatic nerve; Nociception","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001999284,0.000590905,0.0003917296,0.0003125175,0.0002525178,0.0003514763,0.0002215663,0.0005468514,0.001865556],"category_scores_gemma":[0.00009032094,0.0001715207,0.000483024,0.0001539858,0.0003046563,0.0004261238,0.0003967162,0.0006918134,0.0004657782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000195439,"about_ca_system_score_gemma":0.0002148783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000221587,"about_ca_topic_score_gemma":0.000218525,"domain_scores_codex":[0.9998166,0.00003676211,0.00001672436,0.00003941322,0.00003419855,0.00005635043],"domain_scores_gemma":[0.9999144,0.000005930347,0.00002836594,0.000007802144,0.00001725072,0.000026253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006907608,0.000076189,0.001051806,0.000315795,0.00001986103,0.00032538,0.00003092621,0.00005591101,0.9936486,0.0002426258,0.0000911099,0.003450953],"study_design_scores_gemma":[0.000191178,0.003153807,0.105603,0.000272239,0.0002413897,0.006139333,0.0004379853,0.001719385,0.8660537,0.001337735,0.01478461,0.00006560423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9533858,0.03394112,0.0073004,0.000511892,0.0001759765,0.00007087149,0.0004294134,0.00009370288,0.00409079],"genre_scores_gemma":[0.9820607,0.009927847,0.002068693,0.0002609113,0.0000892509,0.0001097348,0.0004168619,0.00001345267,0.005052705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001865556,"threshold_uncertainty_score":0.006240964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006628172969534788,"score_gpt":0.2585984613105649,"score_spread":0.2519702883410301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}