{"id":"W2115647563","doi":"10.1038/clpt.2014.82","title":"Pharmacogenomics, Lipid Disorders, and Treatment Options","year":2014,"lang":"en","type":"review","venue":"Clinical Pharmacology & Therapeutics","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Pharmacogenomics; Clinical pharmacology; Pharmacodynamics; Pharmacology; Medicine; Bioinformatics; Pharmacogenetics; Adverse effect; Pharmacokinetics; Intensive care medicine; Biology; Gene; Genetics; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009443419,0.0008520595,0.001759551,0.003107785,0.0002805724,0.001160154,0.0007965458,0.001168575,0.004981391],"category_scores_gemma":[0.001065389,0.0002876094,0.0006600724,0.002866952,0.0006128072,0.001209223,0.0007292729,0.002048571,0.002119201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000759109,"about_ca_system_score_gemma":0.001418822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001640713,"about_ca_topic_score_gemma":0.002763304,"domain_scores_codex":[0.9997109,0.00007233104,0.00003698651,0.000045498,0.0001115866,0.00002279451],"domain_scores_gemma":[0.9995762,0.0002373496,0.00005286781,0.00001447919,0.00008479344,0.0000343079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004079616,0.00007765331,0.0002491457,0.0134878,0.0001638407,0.0001909522,0.00006051136,0.0003581436,0.0006077384,0.007681193,0.02417281,0.9529095],"study_design_scores_gemma":[0.0000195738,0.00005996635,0.001236413,0.00828837,0.000151761,0.001211956,0.00008654315,0.0001078562,0.0001998366,0.007422706,0.9811929,0.00002200288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000659354,0.9982487,0.0001002192,0.0005308804,0.0001044827,0.00000343818,0.00001392621,0.000004800466,0.000927552],"genre_scores_gemma":[0.0004079505,0.998755,0.0001461357,0.0002122317,0.0001321876,0.000003956836,0.00002125863,7.72907e-7,0.0003205157],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004981391,"threshold_uncertainty_score":0.01666445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1590056960921193,"score_gpt":0.4827303659860899,"score_spread":0.3237246698939706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}