{"id":"W2115648376","doi":"10.1097/cmr.0b013e32832ccd27","title":"Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients","year":2009,"lang":"en","type":"article","venue":"Melanoma Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Israel Cancer Association","keywords":"Single-nucleotide polymorphism; Mdm2; Odds ratio; Promoter; Allele; Molecular biology; Cohort; Germline mutation; Cancer research; Medicine; Genetics; Biology; Gene; Internal medicine; Genotype; Mutation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009699182,0.0001915631,0.0006270215,0.001182997,0.00008438103,0.000009959156,0.000312772,0.0002013835,0.0003094491],"category_scores_gemma":[0.0002325886,0.0001357527,0.0003264159,0.003148461,0.0001794185,0.0000546294,0.0001956323,0.0004514181,0.00001648019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005104333,"about_ca_system_score_gemma":0.0001791896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004474376,"about_ca_topic_score_gemma":0.0002523865,"domain_scores_codex":[0.9965944,0.0003603384,0.0006971263,0.0004347258,0.001388097,0.0005252876],"domain_scores_gemma":[0.9981645,0.00008593164,0.0002019811,0.0009012434,0.00051099,0.0001353721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00147702,0.001401947,0.2710189,0.00009893331,0.0005519599,0.000136277,0.0007513645,0.00009493376,0.7194581,0.0002370825,0.0006499413,0.004123585],"study_design_scores_gemma":[0.002065707,0.001325666,0.7258083,0.000242503,0.0002945725,0.00001625084,0.00002450798,0.001078767,0.2688199,0.00008493693,0.000130253,0.0001086651],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945077,0.0007250728,0.00002075516,0.002066698,0.00007641425,0.0009557885,0.00006929338,0.00001450719,0.00156381],"genre_scores_gemma":[0.9986997,0.00006645189,0.00009212791,0.00007952643,0.00004898034,0.00002303372,0.0001598905,0.00002503726,0.0008052659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4547894,"threshold_uncertainty_score":0.5535835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02927980186863858,"score_gpt":0.3180594327000561,"score_spread":0.2887796308314175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}