{"id":"W2115648376","doi":"10.1097/cmr.0b013e32832ccd27","title":"Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients","year":2009,"lang":"en","type":"article","venue":"Melanoma Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Israel Cancer Association","keywords":"Single-nucleotide polymorphism; Mdm2; Odds ratio; Promoter; Allele; Molecular biology; Cohort; Germline mutation; Cancer research; Medicine; Genetics; Biology; Gene; Internal medicine; Genotype; Mutation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478815,0.0001907895,0.0002130071,0.0006238801,0.0003443993,0.0001944512,0.0001372834,0.0003035467,0.0009711342],"category_scores_gemma":[0.0007452783,0.0001815718,0.0001840438,0.0003872653,0.0001335088,0.0001190974,0.0001334176,0.0002113982,0.0001506599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009684131,"about_ca_system_score_gemma":0.00008706088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001305729,"about_ca_topic_score_gemma":0.0011466,"domain_scores_codex":[0.9998531,0.00003101882,0.00001550224,0.00004733829,0.00002520593,0.00002788783],"domain_scores_gemma":[0.9996872,0.0000762263,0.0001110102,0.00001856997,0.00003145705,0.00007553061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002781834,0.00004575375,0.9858572,0.00001103153,0.00002640831,0.001510129,0.0001745187,0.00003847924,0.01027293,0.00002019223,0.00004468398,0.001720481],"study_design_scores_gemma":[0.00001073404,0.000313889,0.9923866,0.000007880648,0.00004875856,0.005062448,0.00018698,0.0002495159,0.00145543,0.0000377276,0.0002350573,0.000004939948],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997578,0.00006081372,0.00004326674,0.000007179011,0.000001842564,0.000002417562,0.00003075172,0.000001333564,0.00009460155],"genre_scores_gemma":[0.9998496,0.00002338906,0.0000421367,0.0000064437,0.000002070612,0.000001591321,0.00002577195,6.177441e-7,0.00004839938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001305729,"threshold_uncertainty_score":0.003248811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02927980186863858,"score_gpt":0.3180594327000561,"score_spread":0.2887796308314175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}