{"id":"W2115787145","doi":"10.1128/iai.00573-09","title":"Major Secretory Antigens of the Helminth <i>Fasciola hepatica</i> Activate a Suppressive Dendritic Cell Phenotype That Attenuates Th17 Cells but Fails To Activate Th2 Immune Responses","year":2009,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council; Dublin City University","keywords":"Biology; Immune system; Dendritic cell; Antigen presentation; Antigen; Immunology; Cell biology; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010705,0.0003065469,0.000181685,0.0000987098,0.00009160146,0.0002109502,0.00007936681,0.000179866,0.001199049],"category_scores_gemma":[0.00006074964,0.00008384207,0.0001643122,0.0000772505,0.0001507378,0.000124372,0.0001060425,0.0004768673,0.0003106312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001965893,"about_ca_system_score_gemma":0.0001360968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004612076,"about_ca_topic_score_gemma":0.000706104,"domain_scores_codex":[0.9998543,0.0000237387,0.00001313343,0.00002347977,0.00002678371,0.0000584888],"domain_scores_gemma":[0.9999272,0.0000107551,0.00002241027,0.000009203009,0.000008928458,0.00002151394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001117674,0.00002813006,0.0001936897,0.00002994229,0.000002534551,0.00001866562,0.000006429729,0.00001662799,0.9989823,0.00002502008,0.00003461482,0.0005503107],"study_design_scores_gemma":[0.00002584205,0.0005464377,0.00491961,0.000006802719,0.00001045034,0.0002325492,0.00003968523,0.0002929038,0.9914192,0.00001881197,0.00248503,0.000002646463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972894,0.0005715922,0.0006064906,0.00009192524,0.00001938521,0.00001989092,0.00021539,0.00003606332,0.00114983],"genre_scores_gemma":[0.9964695,0.0004215409,0.000726938,0.00009746995,0.00001112256,0.00002671841,0.0003979018,0.00001291055,0.001835827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001199049,"threshold_uncertainty_score":0.004011154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377097432078471,"score_gpt":0.2596722174634757,"score_spread":0.245901243142691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}