{"id":"W2115792215","doi":"10.1096/fj.13-236075","title":"Translational up‐regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Endoplasmic reticulum; Polycystic kidney disease; Unfolded protein response; Medicine; Disease; Cell biology; Internal medicine; Bioinformatics; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001079613,0.0001376971,0.0001062323,0.00003064178,0.0001406895,0.00004252191,0.000219161,0.00005695382,0.0005040074],"category_scores_gemma":[0.0001224334,0.00009738949,0.0001261827,0.00005457755,0.0001389025,0.000008736543,0.00002787334,0.00009928543,0.00001911023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005894649,"about_ca_system_score_gemma":0.0003268176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001457787,"about_ca_topic_score_gemma":9.091258e-7,"domain_scores_codex":[0.9989832,0.0001210938,0.000271377,0.0001544546,0.0002610073,0.0002088918],"domain_scores_gemma":[0.9990864,0.00001163796,0.0001553171,0.0002254367,0.0001215299,0.0003996649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001730132,0.00007013149,0.002049577,0.00002298699,0.00005329152,8.895262e-7,0.00003311913,0.0001307322,0.9852902,0.00002725334,0.01186355,0.0002852257],"study_design_scores_gemma":[0.0009139326,0.0001202402,0.02339354,0.00006691249,0.00008218563,0.00003100266,0.00008914883,0.0004903052,0.9723386,0.001055015,0.00125271,0.0001664621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942846,0.0008564195,0.002585571,0.001227894,0.0001423593,0.000334954,0.0002904093,0.000005530918,0.0002722332],"genre_scores_gemma":[0.9977256,0.00003689177,0.0001827439,0.0002048822,0.0002131954,0.00002678856,0.0002608923,0.00001683768,0.001332185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02134396,"threshold_uncertainty_score":0.5518528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004844722662754694,"score_gpt":0.2036285855574765,"score_spread":0.1987838628947218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}