{"id":"W2115803302","doi":"10.1016/j.gene.2007.06.020","title":"Establishment of a tissue-specific RNAi system in C. elegans","year":2007,"lang":"en","type":"article","venue":"Gene","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences","keywords":"Biology; RNA interference; Mutant; Gene knockdown; Gene; Complementary DNA; Caenorhabditis elegans; Molecular biology; Gene expression; Phenotype; Cell biology; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003513982,0.000533362,0.0002840623,0.0007928472,0.0005246886,0.0003340241,0.0007846372,0.000460985,0.001476149],"category_scores_gemma":[0.0002586909,0.0003897513,0.000431402,0.000180191,0.0004475718,0.0003100274,0.0003808209,0.001154918,0.0007326926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006724172,"about_ca_system_score_gemma":0.0008593537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002356778,"about_ca_topic_score_gemma":0.005310799,"domain_scores_codex":[0.9997551,0.00001968274,0.00004085634,0.00007329418,0.00007660592,0.00003448204],"domain_scores_gemma":[0.9996622,0.00004910268,0.00007751562,0.00005969857,0.00004766713,0.0001039634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002787283,0.00002382198,0.00006358844,0.00002156877,0.00000313855,0.0000327295,0.000009961135,0.0000440256,0.9985492,0.0003008205,0.00006396243,0.000859466],"study_design_scores_gemma":[0.00001780028,0.0001052299,0.001028307,0.000009127079,0.00001942909,0.0001229635,0.00001020207,0.0008521989,0.9941601,0.00004500752,0.003620802,0.000008847838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9088434,0.001059931,0.07574319,0.0004910839,0.0003585243,0.001365069,0.004012838,0.002040661,0.006085239],"genre_scores_gemma":[0.868908,0.001243359,0.1058166,0.0002521986,0.00004730613,0.001283682,0.004440648,0.000701441,0.01730669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002356778,"threshold_uncertainty_score":0.004938185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008996239462357648,"score_gpt":0.2290266749205339,"score_spread":0.2200304354581763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}