{"id":"W2115836576","doi":"10.1016/s1474-4422(08)70198-4","title":"Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study","year":2008,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":357,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Boehringer Ingelheim (Canada); Population Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; Boehringer Ingelheim","keywords":"Telmisartan; Medicine; Dipyridamole; Clopidogrel; Stroke (engine); Aspirin; Placebo; Regimen; Internal medicine; Modified Rankin Scale; Anesthesia; Ischemic stroke; Ischemia; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001552985,0.002394783,0.005832009,0.0005051356,0.000511546,0.001382369,0.001214694,0.002223359,0.004675982],"category_scores_gemma":[0.001988726,0.001064226,0.002855954,0.0004367501,0.001062991,0.001529737,0.0005057689,0.003315103,0.0008994923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005128173,"about_ca_system_score_gemma":0.0007257427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001262475,"about_ca_topic_score_gemma":0.002224745,"domain_scores_codex":[0.9993615,0.0003078966,0.00005509867,0.0001236833,0.00005087394,0.0001010195],"domain_scores_gemma":[0.9988863,0.0003922684,0.0002045685,0.0001036797,0.00005803747,0.0003552311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9884049,0.003014317,0.0003110828,0.0003729137,0.001067357,0.00002782436,0.00003104357,0.0001400329,0.0008535998,0.00004461573,0.00024122,0.005491022],"study_design_scores_gemma":[0.9470377,0.04845084,0.002578048,0.00002302146,0.001098661,0.00002284699,0.00001963731,0.0002965299,0.000191728,0.0000839108,0.0001779656,0.00001907598],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913507,0.004153033,0.0003668826,0.0004406662,0.0005489257,0.0008819511,0.0007282862,0.0001060718,0.001423549],"genre_scores_gemma":[0.9870591,0.003779881,0.00122519,0.000981815,0.001436337,0.001340229,0.0009840223,0.00002621454,0.003167126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005832009,"threshold_uncertainty_score":0.0156427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805578443052815,"score_gpt":0.2988998280789225,"score_spread":0.2708440436483943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}