{"id":"W2115850616","doi":"10.1183/13993003/erj.42.suppl_57.1786","title":"Effect of macitentan on morbidity and mortality in pulmonary arterial hypertension: A randomised controlled trial (SERAPHIN)","year":2013,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Victoria Hospital; London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Endothelin receptor antagonist; Placebo; Lung transplantation; Pulmonary hypertension; Internal medicine; Clinical endpoint; Bosentan; Cardiology; Endothelin receptor; Randomized controlled trial; Anesthesia; Transplantation; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001020677,0.0008566141,0.001486742,0.0002122987,0.0002010185,0.0005479893,0.0005092992,0.0007315679,0.00336744],"category_scores_gemma":[0.001218117,0.0002630559,0.001112216,0.0001900449,0.0004042234,0.0003650892,0.0002917751,0.001386793,0.0003140593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003410135,"about_ca_system_score_gemma":0.0005251614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009139333,"about_ca_topic_score_gemma":0.002304131,"domain_scores_codex":[0.9996495,0.0002202506,0.00002365691,0.00004619069,0.00002478869,0.00003547711],"domain_scores_gemma":[0.9995938,0.0001310543,0.00009771432,0.00002712795,0.00002949143,0.0001209289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9678208,0.00182369,0.00110683,0.001290283,0.001031957,0.0000633536,0.00004489749,0.0002542658,0.004458046,0.0001289922,0.0006615891,0.02131525],"study_design_scores_gemma":[0.9562126,0.033498,0.007494546,0.00009031643,0.0006779333,0.00005786158,0.00002566963,0.0005160744,0.0005638415,0.00009862686,0.0007506464,0.00001406684],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888286,0.007160925,0.0003370992,0.0004175853,0.0003297324,0.000738829,0.0006489619,0.00006238194,0.001476001],"genre_scores_gemma":[0.9905346,0.004113931,0.000793316,0.0005565858,0.0002997958,0.001226163,0.0007344443,0.000009941945,0.001731242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00336744,"threshold_uncertainty_score":0.01126528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03622084136816274,"score_gpt":0.3019087420614315,"score_spread":0.2656879006932688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}