{"id":"W2115896347","doi":"10.1158/0008-5472.can-09-0496","title":"Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8+ T-Cell Anergy and CD4+ Tr1 Cell Responses","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Apoptosis; CD8; Biology; Cytotoxic T cell; Immune system; Cell biology; Transforming growth factor; Cancer research; CTL*; T cell; Molecular biology; Chemistry; In vitro; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001307288,0.0003327643,0.0005201309,0.0006017758,0.001162738,0.0001467666,0.0002819189,0.0002520061,0.0001769066],"category_scores_gemma":[0.0002253621,0.0002992777,0.00008276878,0.0003562696,0.000754981,0.0004901273,0.0001330256,0.0009542602,0.00002238753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001708131,"about_ca_system_score_gemma":0.0003351471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00151649,"about_ca_topic_score_gemma":0.0001148916,"domain_scores_codex":[0.9966859,0.001189542,0.0004722707,0.0005849794,0.000181757,0.0008855839],"domain_scores_gemma":[0.9984061,0.0007392972,0.00012347,0.0003800401,0.0002581955,0.00009290342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002077831,0.0001324657,0.001257692,0.0001726828,0.00004322777,0.0000147639,0.002477311,0.000001886941,0.9886506,0.0000773528,0.0001251248,0.00496913],"study_design_scores_gemma":[0.001945059,0.0006596671,0.04086926,0.0001816621,0.00003011695,0.00009200214,0.0008334602,0.000008417817,0.9534182,0.0002102446,0.001418051,0.0003338709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727478,0.0254292,0.00001931532,0.000523556,0.0001546896,0.0004862106,0.00006030051,0.00006322662,0.0005157106],"genre_scores_gemma":[0.9935775,0.0035888,0.00002600931,0.0000992628,0.00005346381,0.00004376606,0.00003378687,0.0000349537,0.002542407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03961157,"threshold_uncertainty_score":0.9999459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04897837990844208,"score_gpt":0.3304775497277957,"score_spread":0.2814991698193536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}