{"id":"W2115896347","doi":"10.1158/0008-5472.can-09-0496","title":"Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8+ T-Cell Anergy and CD4+ Tr1 Cell Responses","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Apoptosis; CD8; Biology; Cytotoxic T cell; Immune system; Cell biology; Transforming growth factor; Cancer research; CTL*; T cell; Molecular biology; Chemistry; In vitro; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000789737,0.0002876302,0.000161808,0.0001559647,0.00005826376,0.0001478901,0.00009176513,0.0001540976,0.000951372],"category_scores_gemma":[0.00006722725,0.00008844712,0.0001622343,0.00006554666,0.0001318925,0.0001014073,0.000111591,0.0005263709,0.0002549301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001065644,"about_ca_system_score_gemma":0.0001061041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001040064,"about_ca_topic_score_gemma":0.0001730265,"domain_scores_codex":[0.9999192,0.00001444487,0.000006273553,0.00001006892,0.00002317009,0.00002689685],"domain_scores_gemma":[0.999948,0.00001181354,0.00001377982,0.000007263769,0.000006992951,0.00001198119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008455342,0.00003885792,0.0001889937,0.00002056791,0.000003470531,0.00001560412,0.000008391203,0.00004230863,0.9980671,0.00004551248,0.00001035774,0.001474244],"study_design_scores_gemma":[0.000029721,0.0005924841,0.00419603,0.000007557868,0.0000155207,0.000179145,0.00001754039,0.0006881043,0.9928652,0.00005833291,0.001348892,0.000001428162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964029,0.000957215,0.001354205,0.00003032941,0.0000104116,0.00001519285,0.00005471116,0.00003546977,0.001139502],"genre_scores_gemma":[0.9969562,0.0005492577,0.0007892583,0.00002792553,0.000006339839,0.0000198745,0.0001861586,0.000007519059,0.001457542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000951372,"threshold_uncertainty_score":0.003182709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04897837990844208,"score_gpt":0.3304775497277957,"score_spread":0.2814991698193536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}