{"id":"W2115939502","doi":"10.1161/hypertensionaha.113.01295","title":"Increased Renal Epithelial Na Channel Expression and Activity Correlate With Elevation of Blood Pressure in Spontaneously Hypertensive Rats","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Epithelial sodium channel; Blood pressure; Endocrinology; Internal medicine; Kidney; Renin–angiotensin system; Spontaneously hypertensive rat; Aldosterone; Renal medulla; Sodium; Medicine; Biology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009496908,0.0001508878,0.0002068562,0.00006376654,0.00004979625,0.00000827952,0.00004923363,0.0001896621,0.000009417955],"category_scores_gemma":[0.00003153374,0.0001154538,0.00003262377,0.00007352182,0.00005741448,0.000017472,0.00002443055,0.00008615883,0.000001575384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003079145,"about_ca_system_score_gemma":0.00003481236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002507075,"about_ca_topic_score_gemma":0.00005733941,"domain_scores_codex":[0.9991495,0.00005210801,0.0001645099,0.0002941468,0.0001826846,0.000157076],"domain_scores_gemma":[0.9993604,0.00001411139,0.0001112419,0.0001769995,0.0002783793,0.00005881567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006353303,0.0001115717,0.0006857675,0.00002707022,0.00003223587,0.00002340385,0.00005861793,0.0002433624,0.9974288,0.000002251541,0.00009683405,0.0006547376],"study_design_scores_gemma":[0.001685358,0.0004863551,0.07446233,0.0001364606,0.0001164265,0.0002213924,0.00005809523,0.004376663,0.9181134,0.00003269194,0.0001235107,0.0001873311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988782,0.0003390961,0.0002758612,0.00006742604,0.00005036355,0.0003319332,0.000009081253,0.00000952309,0.00003855212],"genre_scores_gemma":[0.9993686,0.00008333028,0.000161331,0.00008291524,0.00006127425,0.00001958349,0.00009744475,0.00001870145,0.0001068343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07931543,"threshold_uncertainty_score":0.4708069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006751069948459444,"score_gpt":0.1794272050900101,"score_spread":0.1726761351415507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}