{"id":"W2116144836","doi":"10.1517/14712598.2011.538677","title":"Immunotherapy for metastatic prostate cancer: where are we at with sipuleucel-T?","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Prostate cancer; Immunotherapy; Cancer; Clinical trial; Oncology; Clinical endpoint; Internal medicine; Cancer vaccine; Immune system; Cancer immunotherapy; Malignancy; Population; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005124411,0.001478643,0.00330923,0.0002700408,0.0007609841,0.00007425308,0.00103362,0.001560505,0.003268455],"category_scores_gemma":[0.00003281683,0.0007918656,0.001230589,0.0003203518,0.0007260615,0.00009291679,0.00009031365,0.001279008,0.0003311626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002200538,"about_ca_system_score_gemma":0.0002754433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002836235,"about_ca_topic_score_gemma":0.00000481578,"domain_scores_codex":[0.9950711,0.001319431,0.001090139,0.001315313,0.0001162411,0.00108781],"domain_scores_gemma":[0.9960697,0.00144593,0.001162787,0.001111803,0.0001474178,0.00006241102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008722072,0.0005614189,0.00000649059,0.0002121684,0.001662691,0.000004589308,0.0002595543,4.318184e-7,0.00692399,0.0001297225,0.009688526,0.9718283],"study_design_scores_gemma":[0.00462782,0.003715132,0.00001083729,0.004811959,0.000009268216,0.0001251688,0.00008119607,1.693987e-7,0.001902792,0.00004012953,0.9834865,0.001189012],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001590981,0.9906093,0.00003912274,0.001120735,0.00286708,0.004251109,0.0006071986,0.0002748252,0.00007148429],"genre_scores_gemma":[0.00001067826,0.9891289,0.0002418395,0.000879408,0.0002575807,0.005517864,0.001035324,0.0002217973,0.002706541],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.973798,"threshold_uncertainty_score":0.9997963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.113076591798333,"score_gpt":0.378021136441841,"score_spread":0.264944544643508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}