{"id":"W2116186946","doi":"10.1096/fj.09-145789","title":"WNT4 is required for normal ovarian follicle development and female fertility","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs","keywords":"WNT4; Antral follicle; Wnt signaling pathway; Ovary; Follicle; Biology; Folliculogenesis; Ovarian follicle; Internal medicine; Endocrinology; Andrology; Ovarian reserve; SOX9; Cell biology; Gene expression; Medicine; Gene; Signal transduction; Genetics; Infertility; Embryo; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001643773,0.0002978531,0.0003133806,0.0004726246,0.000239455,0.0004803593,0.0002905648,0.0003877032,0.001811145],"category_scores_gemma":[0.0003211462,0.0003084133,0.0003530536,0.0002143659,0.0002822051,0.0001852411,0.0003484655,0.0003598616,0.0007880541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004304617,"about_ca_system_score_gemma":0.0005062037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001835085,"about_ca_topic_score_gemma":0.002431266,"domain_scores_codex":[0.9997365,0.00003156701,0.00003094883,0.00004201509,0.00009675149,0.0000621076],"domain_scores_gemma":[0.9996165,0.00003203359,0.0001837268,0.00003258419,0.00004276886,0.0000923183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002040283,0.00001207788,0.001185,0.00004491676,0.00001102414,0.0002007583,0.00001568812,0.00007929802,0.9962379,0.0001532781,0.00007558874,0.001780415],"study_design_scores_gemma":[0.0001137198,0.0002970402,0.07695705,0.00003613634,0.00007355998,0.00250042,0.000124284,0.001694537,0.9027693,0.0003057181,0.01510771,0.000020487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861736,0.003761518,0.004470992,0.0002472046,0.00004137429,0.00003905839,0.001686585,0.0003049418,0.003274702],"genre_scores_gemma":[0.9843853,0.001898984,0.00340787,0.00009524368,0.00001873618,0.00006318374,0.002456859,0.0001165951,0.007557352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001835085,"threshold_uncertainty_score":0.006058872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03956909544151975,"score_gpt":0.2926300733869057,"score_spread":0.2530609779453859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}