{"id":"W2116186946","doi":"10.1096/fj.09-145789","title":"WNT4 is required for normal ovarian follicle development and female fertility","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs","keywords":"WNT4; Antral follicle; Wnt signaling pathway; Ovary; Follicle; Biology; Folliculogenesis; Ovarian follicle; Internal medicine; Endocrinology; Andrology; Ovarian reserve; SOX9; Cell biology; Gene expression; Medicine; Gene; Signal transduction; Genetics; Infertility; Embryo; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001409642,0.00009727087,0.0001662263,0.00002602747,0.0004466607,0.00002168136,0.00009744707,0.00008708471,0.0001646331],"category_scores_gemma":[0.0002030068,0.00005650416,0.00006718173,0.0000485873,0.0001883014,0.000079972,0.00003875863,0.000387618,0.00001192592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002232039,"about_ca_system_score_gemma":0.0001452483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006275869,"about_ca_topic_score_gemma":0.00001154732,"domain_scores_codex":[0.9991974,0.00004631929,0.0002332667,0.0001918381,0.0001062751,0.0002249304],"domain_scores_gemma":[0.999317,0.00005693959,0.00007895572,0.0002765538,0.0001306581,0.0001398415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.009457218,0.0002438124,0.2234236,0.0000452157,0.0002596595,0.00001769849,0.003811065,1.753336e-7,0.7167477,0.0001345182,0.0007836033,0.04507569],"study_design_scores_gemma":[0.000921578,0.0001165522,0.7435125,0.000007971803,0.00004627711,0.0003035265,0.000129535,0.00002513173,0.2470932,0.0005313433,0.007252685,0.00005968686],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945861,0.0001441375,0.0007581663,0.003308077,0.0003676058,0.0002787305,0.000005398804,0.00001427999,0.0005374956],"genre_scores_gemma":[0.9946471,0.000005521388,0.003486738,0.0006026155,0.0003246117,0.00001093294,0.000003283742,0.000007057349,0.0009120831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5200889,"threshold_uncertainty_score":0.3435398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03956909544151975,"score_gpt":0.2926300733869057,"score_spread":0.2530609779453859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}