{"id":"W2116187144","doi":"10.4049/jimmunol.1001413","title":"Regulation of Follicular B Cell Differentiation by the Related E26 Transformation-Specific Transcription Factors PU.1, Spi-B, and Spi-C","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Transcription factor; Follicular phase; Cell biology; Chemistry; Transcription (linguistics); Endocrinology; Internal medicine; Biology; Gene; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471185,0.0003604127,0.0001586557,0.0004011476,0.0001697013,0.0002912226,0.0001516281,0.0001834381,0.001205864],"category_scores_gemma":[0.0001545205,0.0001403789,0.0002282537,0.0001199069,0.0003561947,0.0001385299,0.000273441,0.0004914627,0.0004035685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002844504,"about_ca_system_score_gemma":0.0001659251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006013583,"about_ca_topic_score_gemma":0.000494222,"domain_scores_codex":[0.9998296,0.0000298089,0.00001082438,0.00003373184,0.0000426954,0.00005326],"domain_scores_gemma":[0.9998161,0.00003037859,0.00005700317,0.00001668818,0.00002355553,0.00005621884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007253083,0.00002504333,0.0003683843,0.00001207804,0.000001607955,0.00003425565,0.00001388015,0.00004262721,0.9981071,0.000116205,0.00002519617,0.001180924],"study_design_scores_gemma":[0.00002731775,0.000284403,0.0160571,0.000006479184,0.00000755472,0.0003303083,0.00005446956,0.001232194,0.9790536,0.0001443891,0.002794826,0.000007304709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994428,0.0009579718,0.002565747,0.00005032829,0.000006631969,0.00002063904,0.0002365299,0.0001233768,0.001610825],"genre_scores_gemma":[0.9952226,0.0005673138,0.001842542,0.0000259594,0.000006240139,0.00003348068,0.0004011056,0.00002483265,0.001875883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001205864,"threshold_uncertainty_score":0.004033983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006528225340561029,"score_gpt":0.18705259240728,"score_spread":0.180524367066719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}