{"id":"W2116196682","doi":"10.1128/mcb.25.21.9175-9188.2005","title":"A Human Protein Complex Homologous to the <i>Drosophila</i> MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":335,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genome Canada","keywords":"Biology; Histone H4; Acetylation; Histone; Lysine; Chromodomain; Chromatin; Histone H3; Bromodomain; Histone methyltransferase; Cell biology; Molecular biology; Genetics; Gene; RNA; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007185643,0.0004730746,0.0002029361,0.000360271,0.0003801767,0.0004292469,0.0001934486,0.0002763552,0.003532446],"category_scores_gemma":[0.000123611,0.0001538435,0.0003046882,0.0002497673,0.0002209263,0.0002018739,0.0003343465,0.0002450604,0.002181271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001001682,"about_ca_system_score_gemma":0.0002363816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001873871,"about_ca_topic_score_gemma":0.002775948,"domain_scores_codex":[0.9998895,0.00000682384,0.000006552992,0.00004219818,0.00003475331,0.00002008597],"domain_scores_gemma":[0.9999152,0.00000582057,0.00002770051,0.00001056364,0.000010764,0.00002993138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001210141,0.00001646885,0.002276852,0.0000574193,0.00002883341,0.0001515623,0.00002518634,0.0001063577,0.9869933,0.0005670979,0.0008834504,0.008772415],"study_design_scores_gemma":[0.0000377649,0.000188353,0.03796815,0.00001263864,0.00004285442,0.001986618,0.00004616048,0.001476939,0.8844478,0.0004085633,0.07336755,0.00001666449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630324,0.006685084,0.01716688,0.0004976582,0.0001431622,0.00009826014,0.003150782,0.001213217,0.008012597],"genre_scores_gemma":[0.9673768,0.0008576987,0.01080157,0.0001954341,0.00003650596,0.00003835677,0.006386257,0.00008372075,0.01422355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003532446,"threshold_uncertainty_score":0.01181722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529938589159358,"score_gpt":0.2778564781046028,"score_spread":0.2625570922130092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}