{"id":"W2116204780","doi":"10.1128/iai.68.9.5126-5131.2000","title":"Interleukin 18 Restores Defective Th1 Immunity to<i>Candida albicans</i>in Caspase 1-Deficient Mice","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Biology; Candida albicans; Caspase 1; Tumor necrosis factor alpha; Immune system; Interleukin; Immunity; Microbiology; Immunology; Caspase; Cytokine; Interferon gamma; Interleukin 15; Inflammation; Caspase 3; Apoptosis; Programmed cell death; Inflammasome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001879298,0.001023458,0.0004899662,0.000899069,0.0002114821,0.0006181399,0.000372588,0.0006607478,0.001906831],"category_scores_gemma":[0.0002567312,0.0003836299,0.0004014565,0.000224,0.0005876609,0.0003710319,0.0002587003,0.001545652,0.0007389932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004016734,"about_ca_system_score_gemma":0.0003292299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000457416,"about_ca_topic_score_gemma":0.000511737,"domain_scores_codex":[0.9997321,0.00003674449,0.00003906379,0.00006119777,0.00005424935,0.00007664465],"domain_scores_gemma":[0.9992981,0.00007197975,0.0003638607,0.00005640538,0.00004067895,0.0001690761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004050318,0.0001196114,0.0001673943,0.00005177524,0.000009415797,0.0001360139,0.00002169053,0.0001295968,0.9967737,0.0002390921,0.00007695096,0.001869682],"study_design_scores_gemma":[0.0002753107,0.001399578,0.004189154,0.00003849345,0.00004812778,0.001605065,0.00005730674,0.001430389,0.9869382,0.0003063896,0.003693518,0.00001841059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920501,0.001255828,0.003302791,0.000276524,0.00009140055,0.00004538683,0.001012557,0.0005029293,0.001462383],"genre_scores_gemma":[0.987102,0.001363144,0.005299813,0.0001492065,0.00004793567,0.00006894525,0.001060368,0.0002217218,0.00468703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001906831,"threshold_uncertainty_score":0.006379008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007716974144099218,"score_gpt":0.2496345301490447,"score_spread":0.2419175560049455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}