{"id":"W2116204780","doi":"10.1128/iai.68.9.5126-5131.2000","title":"Interleukin 18 Restores Defective Th1 Immunity to<i>Candida albicans</i>in Caspase 1-Deficient Mice","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Biology; Candida albicans; Caspase 1; Tumor necrosis factor alpha; Immune system; Interleukin; Immunity; Microbiology; Immunology; Caspase; Cytokine; Interferon gamma; Interleukin 15; Inflammation; Caspase 3; Apoptosis; Programmed cell death; Inflammasome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003084275,0.0001903562,0.0001659975,0.0001246691,0.0002423722,0.000042754,0.0001228066,0.0001368136,0.0003636658],"category_scores_gemma":[0.0001016579,0.000192743,0.00008447155,0.0002345144,0.0001073278,0.00001504184,0.0001030896,0.0002794563,0.00004780411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004947746,"about_ca_system_score_gemma":0.00005165465,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009192699,"about_ca_topic_score_gemma":0.003518726,"domain_scores_codex":[0.9988898,0.0002587302,0.0002370504,0.0002581527,0.00007999966,0.0002762848],"domain_scores_gemma":[0.9994192,0.00002173707,0.00004715722,0.000368648,0.00006901448,0.00007425117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002037642,0.001065187,0.08976849,0.00006750285,0.0001833918,0.0000128047,0.004393963,0.0009846097,0.8037113,0.0001024029,0.003553132,0.0941196],"study_design_scores_gemma":[0.002187875,0.001400589,0.627031,0.00007878007,0.00003240907,0.00006158931,0.001028575,0.00006517575,0.1565722,0.0001128341,0.2107638,0.0006653078],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986321,0.0005575758,0.0000763951,0.00006862415,0.0001517169,0.0002502488,0.00000886861,0.0000215521,0.01254404],"genre_scores_gemma":[0.9975781,0.0008442017,0.000021607,0.0004790881,0.00003827038,0.00004214383,0.00007208734,0.00001756413,0.0009069139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6471391,"threshold_uncertainty_score":0.9974052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007716974144099218,"score_gpt":0.2496345301490447,"score_spread":0.2419175560049455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}