{"id":"W2116227836","doi":"10.1128/jvi.05996-11","title":"CD8 <sup>+</sup> T Cell Immunodominance in Lymphocytic Choriomeningitis Virus Infection Is Modified in the Presence of Toll-Like Receptor Agonists","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Immunodominance; Lymphocytic choriomeningitis; Biology; Epitope; Virology; Subdominant; Toll-like receptor; Cytotoxic T cell; Antigen; CD8; TLR2; TLR3; Antigen presentation; T cell; Immunology; Immune system; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001874032,0.0002723345,0.0001977601,0.000137187,0.0001375271,0.0003214173,0.0001211207,0.0002396336,0.001043492],"category_scores_gemma":[0.000154946,0.0001267054,0.0001293635,0.00008558154,0.000251382,0.000175986,0.0001615156,0.0006850544,0.0003677217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001559644,"about_ca_system_score_gemma":0.00009007727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001515604,"about_ca_topic_score_gemma":0.0002138531,"domain_scores_codex":[0.9997937,0.00005763566,0.00002167945,0.00002344841,0.00003784163,0.00006567382],"domain_scores_gemma":[0.999894,0.00002251554,0.00002219135,0.00001601792,0.00001116139,0.00003404684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002416055,0.00001789214,0.0001300017,0.000009295743,0.000001191742,0.00002588816,0.000007688449,0.00001456555,0.9991856,0.00001699143,0.000007076652,0.000342292],"study_design_scores_gemma":[0.00006047187,0.0007725583,0.01264118,0.000005844465,0.00001599549,0.0004800997,0.00007200846,0.0008653233,0.9839652,0.00009102636,0.001025178,0.00000516313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988601,0.0002997959,0.0003161757,0.00002772975,0.00001040746,0.00000624107,0.00004209171,0.0000101782,0.0004272262],"genre_scores_gemma":[0.9985707,0.0001433368,0.0004822432,0.00003997115,0.000009408004,0.00001888836,0.0001004852,0.000009505558,0.0006255367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001043492,"threshold_uncertainty_score":0.003490865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01616934735493562,"score_gpt":0.2296414734438456,"score_spread":0.2134721260889099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}