{"id":"W2116235942","doi":"10.1097/01.asn.0000094082.11026.ee","title":"Ureteric Bud Apoptosis and Renal Hypoplasia in Transgenic PAX2-Bax Fetal Mice Mimics the Renal-Coloboma Syndrome","year":2003,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; Montreal Children's Hospital; McGill University","funders":"Health Research Council of New Zealand; Canadian Institutes of Health Research; Royal Society","keywords":"Ureteric bud; Biology; Kidney; Apoptosis; Haploinsufficiency; Endocrinology; Internal medicine; Nephron; Hypoplasia; Coloboma; Kidney development; Pathology; Embryonic stem cell; Anatomy; Medicine; Phenotype; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001291861,0.0004481507,0.0001887911,0.0006618208,0.0001917283,0.0003419394,0.0002172706,0.0006160911,0.001356504],"category_scores_gemma":[0.0001599851,0.0004130821,0.0003027701,0.0002098473,0.0003467121,0.0002009517,0.0002172768,0.0006100089,0.0003122965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002839965,"about_ca_system_score_gemma":0.0001759689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004867924,"about_ca_topic_score_gemma":0.0008548464,"domain_scores_codex":[0.9998234,0.00002432396,0.00002242205,0.00005429515,0.00005240845,0.00002311636],"domain_scores_gemma":[0.9998044,0.00003284013,0.00008870158,0.0000213238,0.000009270982,0.00004343181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000134072,0.00003488811,0.0007849935,0.0000203957,0.000008616296,0.0008752126,0.00003064824,0.0001212339,0.9964582,0.0003626,0.00003495063,0.001134054],"study_design_scores_gemma":[0.00009883888,0.0006439544,0.02372709,0.00001242287,0.0000489113,0.01204294,0.00007492943,0.002825486,0.956548,0.0004108342,0.003552073,0.00001452404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931345,0.0006275356,0.004271146,0.0001052058,0.0000247758,0.0000298492,0.0002650903,0.000216766,0.001325135],"genre_scores_gemma":[0.9927867,0.0005452697,0.002926116,0.00004391244,0.000009297943,0.0000358135,0.0003408449,0.00003412886,0.003277974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001356504,"threshold_uncertainty_score":0.004538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006171745339103991,"score_gpt":0.2200895258136905,"score_spread":0.2139177804745865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}