{"id":"W2116323280","doi":"10.1016/j.cytogfr.2008.01.002","title":"Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis","year":2008,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":364,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Versus Arthritis","keywords":"CTGF; Growth factor; Cell biology; Extracellular matrix; Fibrosis; Connective tissue; CYR61; Angiogenesis; Biology; Cancer research; Chondrogenesis; Mesenchymal stem cell; Chemistry; Pathology; Receptor; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004495671,0.001019939,0.00297608,0.0005846831,0.000145653,0.00005095442,0.0003596983,0.0007912781,0.0001193393],"category_scores_gemma":[0.001500462,0.0009067079,0.000471118,0.0007213525,0.0003184906,0.00005158781,0.0005124255,0.0005792676,0.00002740704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001874103,"about_ca_system_score_gemma":0.0002014595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000207733,"about_ca_topic_score_gemma":0.0001030281,"domain_scores_codex":[0.9948617,0.0009644197,0.001553405,0.001581081,0.000407879,0.0006315205],"domain_scores_gemma":[0.9973775,0.0002510447,0.0009092868,0.0008342331,0.0003399866,0.0002879715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001232331,0.0001319875,0.004235207,0.02243578,0.0002987761,0.00001904134,0.0001770787,1.130103e-7,0.01885999,0.0001584686,0.0007344391,0.9528259],"study_design_scores_gemma":[0.0007424793,0.001001718,0.01041524,0.005439318,0.0002136456,0.0001137618,0.00001265304,0.000001811137,0.0078773,0.00004187424,0.9732274,0.0009127625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01304159,0.9827504,0.0001908799,0.0000138689,0.0001705285,0.003234972,0.0003413857,0.00004422004,0.0002121436],"genre_scores_gemma":[0.02308768,0.9752494,0.0002113723,0.00001533913,0.0003093467,0.0003020677,0.0004617607,0.0001471781,0.0002158609],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.972493,"threshold_uncertainty_score":0.9993383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05026127976184044,"score_gpt":0.3357064141219172,"score_spread":0.2854451343600768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}