{"id":"W2116332104","doi":"10.1002/jps.21250","title":"Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Pyrazinamide**A project of the International Pharmaceutical Federation FIP, Groupe BCS, www.fip.org/bcs.**This article reflects the scientific opinion of the authors and not the policies of regulating agencies.","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Bioequivalence; Dosage form; Medicine; Active ingredient; Pharmacology; Dosing; Dissolution testing; Drug; Immediate release; Pyrazinamide; Expert opinion; Biopharmaceutics Classification System; Intensive care medicine; Pharmacokinetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002427442,0.0009202356,0.0004688538,0.002944456,0.0009234819,0.0009222755,0.001329937,0.002052756,0.03213707],"category_scores_gemma":[0.002456926,0.0004905933,0.0003235148,0.001546746,0.000466,0.0008695824,0.0005495012,0.001735802,0.02010515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007671414,"about_ca_system_score_gemma":0.003282557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003336747,"about_ca_topic_score_gemma":0.008437002,"domain_scores_codex":[0.9987275,0.0002454961,0.0001456765,0.00008087925,0.0007265923,0.00007373577],"domain_scores_gemma":[0.9959091,0.0007938443,0.0008028193,0.0002887259,0.001884623,0.0003209264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002930106,0.0004905084,0.0005106204,0.001229739,0.0000136057,0.0002913553,0.0001424544,0.0004212937,0.03531889,0.004542229,0.4863389,0.4704074],"study_design_scores_gemma":[0.00002388262,0.0002574679,0.001527227,0.00009993346,0.000008972953,0.0002908608,0.0000151586,0.000156421,0.00577527,0.0003606932,0.9914747,0.000009423899],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.03659836,0.1464559,0.0653941,0.05365149,0.02124164,0.006100888,0.0167409,0.006038595,0.6477782],"genre_scores_gemma":[0.0426846,0.05030138,0.02092462,0.007055298,0.00573549,0.001422596,0.00740638,0.0008948958,0.8635747],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.03213707,"threshold_uncertainty_score":0.1075092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2624358118171178,"score_gpt":0.4762894166106461,"score_spread":0.2138536047935283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}