{"id":"W2116350538","doi":"10.1021/jo062543i","title":"Combined Directed <b><i>ortho</i></b> Metalation/Suzuki−Miyaura Cross-Coupling Strategies. Regiospecific Synthesis of Chlorodihydroxybiphenyls and Polychlorinated Biphenyls","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Metalation; Combinatorial chemistry; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001597202,0.0004113998,0.0006977536,0.00007339877,0.000259904,0.00012193,0.0007502406,0.0003122,0.003487982],"category_scores_gemma":[0.0008593987,0.0003362603,0.000232412,0.0007029999,0.0004779039,0.0003702857,0.0001558905,0.0007208689,0.000003532161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001570132,"about_ca_system_score_gemma":0.0002618119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009738172,"about_ca_topic_score_gemma":0.000003279248,"domain_scores_codex":[0.9970798,0.00001250482,0.001491748,0.0002961631,0.0006814279,0.0004383095],"domain_scores_gemma":[0.9957202,0.001037812,0.001663275,0.0006324339,0.00069883,0.000247451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004279137,0.00016759,0.003358438,0.0003876305,0.0003103332,0.00002691608,0.0003397973,0.00005129985,0.9944121,0.00002992357,0.0000396898,0.0004483964],"study_design_scores_gemma":[0.001128591,0.00002280592,0.004056092,0.0001664278,0.0003351874,0.0003415148,0.001205697,0.0001329026,0.9915996,0.0002017176,0.0004771804,0.000332277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924297,0.001085801,0.0002387163,0.0001763801,0.0001011878,0.00006164213,0.00001970772,0.00008910292,0.005797807],"genre_scores_gemma":[0.9979359,0.0004025377,0.00014927,0.00001328486,0.0003280547,0.000001562707,0.00001085293,0.00006669485,0.00109186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005506227,"threshold_uncertainty_score":0.9999089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051508446267949,"score_gpt":0.2421385899291571,"score_spread":0.2316235054664776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}