{"id":"W2116359866","doi":"10.1111/j.1365-2958.2004.03921.x","title":"Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, <i>Cryptococcus neoformans</i>","year":2004,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; University of British Columbia","keywords":"Cryptococcus neoformans; Biology; Microbiology; Virulence; Peroxidase; Nitric oxide; Pathogen; Fungal pathogen; Peroxide; Fungus; Enzyme; Biochemistry; Botany; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071873,0.0002573878,0.0001360998,0.0001392052,0.000147486,0.0002521319,0.0001172437,0.0001968934,0.000609607],"category_scores_gemma":[0.0001258765,0.00009356059,0.0001295575,0.0001050743,0.0002020849,0.0001299532,0.0001370648,0.0002122959,0.0001457741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003501297,"about_ca_system_score_gemma":0.00021391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001415368,"about_ca_topic_score_gemma":0.00128116,"domain_scores_codex":[0.9999299,0.000008824908,0.000003953468,0.00001600799,0.00001891987,0.00002241232],"domain_scores_gemma":[0.9999226,0.000008336737,0.0000303163,0.000006023039,0.00001280072,0.00001992975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001180353,0.00001228536,0.0008954515,0.00001681191,0.000002695064,0.00005501855,0.00001048562,0.00002860363,0.9974858,0.00006833927,0.00002515627,0.001281273],"study_design_scores_gemma":[0.00001265776,0.0002229653,0.04086526,0.000007923639,0.00001979764,0.0009974338,0.00007761853,0.0006960056,0.9551853,0.0001696823,0.001741035,0.000004352592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977368,0.0007441064,0.0009506184,0.00009820395,0.000008974124,0.00000523988,0.00009762846,0.00002603551,0.0003324279],"genre_scores_gemma":[0.9974205,0.0003499919,0.0009759445,0.00001698977,0.000003234475,0.000004084251,0.0002130878,0.000005935776,0.001010226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001415368,"threshold_uncertainty_score":0.002814293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00992250660632928,"score_gpt":0.2748010628351811,"score_spread":0.2648785562288519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}