{"id":"W2116382435","doi":"10.1038/nature09671","title":"Oncogenically active MYD88 mutations in human lymphoma","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":1509,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Cancer research; Diffuse large B-cell lymphoma; Biology; Lymphoma; Mutation; Mutant; Ibrutinib; Gene; Genetics; Leukemia; Immunology; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002707322,0.00012248,0.0001836087,0.0004684263,0.0001846555,0.0003921801,0.0001671117,0.0003589196,0.0008644509],"category_scores_gemma":[0.0005083464,0.0001562908,0.0001044905,0.0003534837,0.000294361,0.0002325877,0.0002771774,0.0002086828,0.0001990922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003625082,"about_ca_system_score_gemma":0.0001162421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002541554,"about_ca_topic_score_gemma":0.0003172459,"domain_scores_codex":[0.999867,0.00003539773,0.00001740717,0.00001769042,0.00003755799,0.00002498992],"domain_scores_gemma":[0.9998895,0.00003265871,0.00003811997,0.0000133996,0.00001166625,0.00001462288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002829422,0.0001856233,0.282852,0.0003134159,0.00009422156,0.01634333,0.0003839746,0.001692817,0.4688966,0.006054714,0.005259787,0.2150941],"study_design_scores_gemma":[0.0003258318,0.0009210144,0.6323898,0.0001394318,0.0002925702,0.1262486,0.0007237096,0.004343919,0.1702673,0.004898567,0.05941575,0.00003345448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853795,0.007392093,0.0006720699,0.0005774189,0.00004397543,0.000009178173,0.0001334163,0.00004036479,0.005752144],"genre_scores_gemma":[0.9979025,0.001193497,0.0003147554,0.00006208247,0.00001974759,0.00000354125,0.00007427671,0.000005518479,0.0004241006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008644509,"threshold_uncertainty_score":0.002891839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007723989715644191,"score_gpt":0.3081169940131739,"score_spread":0.3003930042975297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}