{"id":"W2116414085","doi":"10.21083/surg.v1i1.294","title":"Design of a novel polydactyl zinc finger with binding specificity for the proximal promoter region of PLN in the proposed treatment of cardiomyopathy.","year":2007,"lang":"en","type":"article","venue":"SURG Journal","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Zinc finger; Phospholamban; Cardiomyopathy; Cell biology; Transcription factor; Biology; Medicine; Cancer research; Endoplasmic reticulum; Chemistry; Gene; Heart failure; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002253663,0.0003309655,0.000341708,0.000148702,0.0001462866,0.0001995806,0.000584855,0.0005022417,0.001133408],"category_scores_gemma":[0.000126825,0.0001516773,0.0003292679,0.0001330399,0.0001982698,0.0001502586,0.0001935785,0.0005245263,0.0004766942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003726437,"about_ca_system_score_gemma":0.0002575694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000534203,"about_ca_topic_score_gemma":0.0007704044,"domain_scores_codex":[0.9998674,0.00001774067,0.00001146584,0.00004103471,0.00003455927,0.00002779477],"domain_scores_gemma":[0.9999365,0.000005933346,0.00001882858,0.000003814844,0.000008254384,0.00002677187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002764009,0.0001146888,0.0002069068,0.0001053903,0.00001722933,0.0001500274,0.00001086612,0.0005490754,0.9913269,0.0003731105,0.0001981371,0.006671282],"study_design_scores_gemma":[0.0003774872,0.001581073,0.001700156,0.00002096797,0.00008262459,0.0008363607,0.00001705787,0.003701618,0.9701321,0.0001299685,0.02139007,0.00003054006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8988167,0.007613324,0.08564469,0.0007316918,0.0004706079,0.0008366015,0.0009053764,0.0004155848,0.004565402],"genre_scores_gemma":[0.9426779,0.001897141,0.04895063,0.0004146528,0.0000311553,0.000274194,0.0008645825,0.0000294072,0.004860301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001133408,"threshold_uncertainty_score":0.00379163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07653336687301836,"score_gpt":0.2964563410953479,"score_spread":0.2199229742223295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}