{"id":"W2116414085","doi":"10.21083/surg.v1i1.294","title":"Design of a novel polydactyl zinc finger with binding specificity for the proximal promoter region of PLN in the proposed treatment of cardiomyopathy.","year":2007,"lang":"en","type":"article","venue":"SURG Journal","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Zinc finger; Phospholamban; Cardiomyopathy; Cell biology; Transcription factor; Biology; Medicine; Cancer research; Endoplasmic reticulum; Chemistry; Gene; Heart failure; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001933131,0.0001464618,0.0005248417,0.0001600805,0.0001005721,0.000008628035,0.00008978524,0.00004856967,0.000002115647],"category_scores_gemma":[0.00006249793,0.00006440141,0.000236512,0.0002656381,0.0001845835,0.00004581485,0.00001299714,0.0001374579,7.95783e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009698272,"about_ca_system_score_gemma":0.0001670736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000398544,"about_ca_topic_score_gemma":0.00001079161,"domain_scores_codex":[0.998705,0.00007787648,0.0004676894,0.0001247791,0.0003771507,0.0002474593],"domain_scores_gemma":[0.9986876,0.0004459536,0.000373722,0.0002227738,0.0002340687,0.00003583455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.05562654,0.00737304,0.2612931,0.00107074,0.004136809,0.001505522,0.07330759,0.0005226599,0.4644744,0.0004158437,0.0007458028,0.129528],"study_design_scores_gemma":[0.04152524,0.02533527,0.3184738,0.00317154,0.003462452,0.01584547,0.029036,0.0004797697,0.5563619,0.0001287408,0.005492163,0.0006875748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9525434,0.001177456,0.04376315,0.0004274975,0.0001128126,0.001704729,0.000009396066,0.000004412424,0.0002571201],"genre_scores_gemma":[0.9966693,0.0002001206,0.002760831,0.00001157981,0.0002674368,0.00001774261,0.000001076168,0.00001445832,0.00005747157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1288404,"threshold_uncertainty_score":0.2626213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07653336687301836,"score_gpt":0.2964563410953479,"score_spread":0.2199229742223295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}