{"id":"W2116423396","doi":"10.1093/hmg/ddh104","title":"Gene-specific timing and epigenetic memory in oocyte imprinting","year":2004,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":430,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"Canadian Institutes of Health Research; Lalor Foundation; McGill University; Howard Hughes Medical Institute","keywords":"Genomic imprinting; Biology; Epigenetics; DNA methylation; Genetics; Oocyte; Imprinting (psychology); Methylation; DNMT3B; Gene; Allele; Gene expression; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000279185,0.0002710255,0.0002073211,0.0001413048,0.0001351907,0.0000650713,0.0002123835,0.0002182896,0.000009717786],"category_scores_gemma":[0.00002660358,0.0003206982,0.00008517575,0.0001399411,0.0001203826,0.000003434901,0.0002252699,0.0001560144,0.000008912373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003844489,"about_ca_system_score_gemma":0.00005668535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000027097,"about_ca_topic_score_gemma":0.00006509697,"domain_scores_codex":[0.998256,0.0000750839,0.0004111051,0.0006270966,0.0002050222,0.000425706],"domain_scores_gemma":[0.9991385,0.00000718927,0.0001101944,0.0005333466,0.00007264739,0.0001380982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001248578,0.00004437814,0.001813395,0.0000152842,0.00002176297,0.00002863309,0.0001300422,0.007784076,0.9848238,0.0001469016,0.000002985428,0.005176251],"study_design_scores_gemma":[0.001125007,0.0001984926,0.04162289,0.00002428549,0.00001651964,0.00001200574,0.00005325919,0.00005682066,0.9531472,0.002269674,0.001084696,0.0003891117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700981,0.01754246,0.01105364,0.00004063246,0.00009260671,0.0002773454,0.000003404496,0.00001599288,0.0008757597],"genre_scores_gemma":[0.9888055,0.002010525,0.008736446,0.0001069507,0.0001481194,0.00002119622,0.00005834961,0.00006749405,0.00004538742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03980949,"threshold_uncertainty_score":0.9999245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02033914126497282,"score_gpt":0.2686338935378766,"score_spread":0.2482947522729038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}