{"id":"W2116445953","doi":"10.15252/embj.201591382","title":"The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis","year":2015,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":235,"is_retracted":false,"has_abstract":true,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Institute of Genetics; Deutsche Forschungsgemeinschaft","keywords":"Biology; Transfer RNA; Methyltransferase; Methylation; DNA methylation; Protein biosynthesis; Start codon; Genetics; RNA; Messenger RNA; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008428349,0.0001230383,0.0001187728,0.00002043077,0.0007046154,0.0001468386,0.0004363115,0.00005369138,0.00002250774],"category_scores_gemma":[0.0002415543,0.00006760247,0.000170698,0.0000614965,0.00009727349,0.000009675222,0.00003477862,0.0001128794,0.00001117899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002918753,"about_ca_system_score_gemma":0.0001483198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001108553,"about_ca_topic_score_gemma":0.00001180005,"domain_scores_codex":[0.9990506,0.0001183864,0.0002539449,0.00014936,0.000159171,0.0002685422],"domain_scores_gemma":[0.999114,0.00006973264,0.0001178882,0.0004038291,0.0001727127,0.0001218185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001193817,0.00007258566,0.0001766546,0.00002515179,0.0006250272,0.000009093726,0.001159877,0.0003062309,0.9199525,0.0006790587,0.05849546,0.01730461],"study_design_scores_gemma":[0.0008928017,0.0001146061,0.000528396,0.00002874962,0.0001330389,0.0003623826,0.001558264,0.0001304417,0.8980884,0.001920722,0.0960054,0.0002368009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818625,0.003432024,0.005300366,0.008179839,0.0002951462,0.0001957815,0.00003037884,0.000008188615,0.0006957792],"genre_scores_gemma":[0.9951295,0.001300633,0.0003100047,0.0003099173,0.0006287773,0.00008093385,0.000002564591,0.00002515553,0.002212545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03750994,"threshold_uncertainty_score":0.5419404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04079079692823854,"score_gpt":0.2994699533538316,"score_spread":0.258679156425593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}