{"id":"W2116536307","doi":"10.1002/jcb.21381","title":"P53 mediated regulation of metallothionein transcription in breast cancer cells","year":2007,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Trace Elements in Health","field":"Nursing","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Trichostatin A; Metallothionein; Transfection; Transcription factor; Zinc; Reporter gene; Cancer research; Biology; Cancer cell; Chemistry; Cell culture; Gene expression; Molecular biology; Cell biology; Gene; Cancer; Histone; Histone deacetylase; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009859644,0.0002500945,0.0002159494,0.0002962219,0.0001896085,0.0003130316,0.0001260515,0.0001940834,0.001537449],"category_scores_gemma":[0.0001537952,0.0001307921,0.0001790865,0.0002270023,0.0001599905,0.0001172773,0.0002239899,0.0003014297,0.0006982836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003194855,"about_ca_system_score_gemma":0.0001206641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009388465,"about_ca_topic_score_gemma":0.001106949,"domain_scores_codex":[0.9998538,0.00003370269,0.00001161448,0.00003874711,0.00003509334,0.00002709991],"domain_scores_gemma":[0.9998927,0.00002859938,0.0000210668,0.00002019618,0.00002120491,0.00001617941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008930709,0.00001190877,0.0002156699,0.00002776418,0.000002271769,0.00006144798,0.00002142835,0.00001834399,0.998174,0.00005265024,0.00005362758,0.001271576],"study_design_scores_gemma":[0.00001797982,0.0001565226,0.009305616,0.000006438169,0.000008976673,0.0003290479,0.00005245951,0.0006599274,0.9853849,0.00007246354,0.0040023,0.000003477871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839121,0.006453966,0.004534616,0.0002660479,0.00005866382,0.00004534478,0.001066386,0.0002220024,0.003440896],"genre_scores_gemma":[0.9901609,0.001961981,0.002351748,0.0000585275,0.00001526306,0.00005429432,0.0009659267,0.00001844384,0.004412889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537449,"threshold_uncertainty_score":0.005143285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009887324957637994,"score_gpt":0.2714988693851906,"score_spread":0.2616115444275526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}