{"id":"W2116536307","doi":"10.1002/jcb.21381","title":"P53 mediated regulation of metallothionein transcription in breast cancer cells","year":2007,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Trace Elements in Health","field":"Nursing","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Trichostatin A; Metallothionein; Transfection; Transcription factor; Zinc; Reporter gene; Cancer research; Biology; Cancer cell; Chemistry; Cell culture; Gene expression; Molecular biology; Cell biology; Gene; Cancer; Histone; Histone deacetylase; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001293015,0.0001276486,0.0002772218,0.0001737237,0.00002566376,0.000008526069,0.0001580891,0.0001798634,0.0001300637],"category_scores_gemma":[0.00003207043,0.0001244566,0.000117544,0.0002872975,0.0000527963,0.0001251428,0.000006823279,0.0003279903,0.000001463946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003131611,"about_ca_system_score_gemma":0.00008670636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005644371,"about_ca_topic_score_gemma":0.00001705672,"domain_scores_codex":[0.9980958,0.00005435016,0.0009873777,0.0001293349,0.0004918958,0.0002412877],"domain_scores_gemma":[0.9987095,0.0000619924,0.0007548221,0.0001499409,0.000212019,0.000111728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005512842,0.0001857132,0.002157228,0.0002200039,0.00002652308,0.00001166576,0.000250419,0.0001246002,0.9944093,0.000006134812,0.0001733628,0.001883821],"study_design_scores_gemma":[0.001055973,0.00005255371,0.01599644,0.0002579802,0.00005346088,0.00003406362,0.0001652905,0.00008375519,0.9819872,0.00004595623,0.0001661856,0.0001011687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958858,0.001177104,0.001049629,0.0008502024,0.0007728363,0.00009229184,0.00002034236,0.000008259256,0.0001434901],"genre_scores_gemma":[0.9984758,0.00005702601,0.001030412,0.00005780441,0.0002876575,7.196617e-7,0.00001032684,0.00002031294,0.00005988471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01383922,"threshold_uncertainty_score":0.5075192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009887324957637994,"score_gpt":0.2714988693851906,"score_spread":0.2616115444275526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}