{"id":"W2116548489","doi":"10.1002/chin.200646116","title":"Substituted N‐(2‐Aminophenyl)‐benzamides, (E)‐N‐(2‐Aminophenyl)‐acrylamides and Their Analogues: Novel Classes of Histone Deacetylase Inhibitors.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Association of Nurses in Oncology","funders":"","keywords":"Chemistry; Histone deacetylase; Combinatorial chemistry; Stereochemistry; Organic chemistry; Medicinal chemistry; Histone; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003521552,0.0005034236,0.0005241794,0.0002953279,0.0001768537,0.00005193101,0.0003992932,0.0004358981,0.00003282487],"category_scores_gemma":[0.0002680449,0.000463305,0.0002153588,0.0003885175,0.000909648,0.00003723674,0.0003144157,0.0002772872,0.00001285132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000137686,"about_ca_system_score_gemma":0.0002910542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005025894,"about_ca_topic_score_gemma":0.0004191097,"domain_scores_codex":[0.9974905,0.000005632763,0.0008131026,0.0006518106,0.0003788946,0.0006601168],"domain_scores_gemma":[0.9982654,0.00007812453,0.0003300643,0.0007616102,0.0003455173,0.0002192156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001354932,0.0002417342,0.0003212577,0.0001971757,0.00006820437,0.000006998929,0.0001767559,0.00001164724,0.976709,0.0003108828,0.01334685,0.008473995],"study_design_scores_gemma":[0.001274787,0.0001649726,0.00111827,0.00007002433,0.00002438019,0.00006898255,0.0002671198,0.00005004579,0.9381061,0.00005548858,0.05832018,0.0004796984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669154,0.003719219,0.00011957,0.00006107439,0.0001793629,0.0003734675,0.0001829589,0.00005722184,0.02839167],"genre_scores_gemma":[0.9922844,0.0002057584,0.0005204509,0.00005808679,0.0004974514,0.00005751774,0.0009103845,0.00006715264,0.005398838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04497333,"threshold_uncertainty_score":0.9997818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01131289290303211,"score_gpt":0.2646362242237518,"score_spread":0.2533233313207197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}