{"id":"W2116554987","doi":"10.1200/jco.2004.04.033","title":"Contralateral Breast Cancer in <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":619,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Breast cancer; Cancer; Oncology; Mutation; Gynecology; Internal medicine; Cancer research; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001047853,0.0001045021,0.0004448071,0.00006006368,0.00002747918,0.00001124165,0.0001325413,0.0003327822,0.00002410556],"category_scores_gemma":[0.0003237143,0.00008915423,0.0001374322,0.00008592712,0.0002156566,0.00001350407,0.00003916197,0.0003566799,0.000001410262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001773842,"about_ca_system_score_gemma":0.001819516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007065966,"about_ca_topic_score_gemma":0.0005624343,"domain_scores_codex":[0.9982485,0.0001638217,0.001083674,0.0001935882,0.0001294302,0.0001809747],"domain_scores_gemma":[0.9987914,0.00008834607,0.0006264335,0.0001089421,0.000223587,0.0001613233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007336028,0.001401989,0.3429661,0.00005979257,0.001208264,0.0008223266,0.001142767,0.02749239,0.07689823,0.0005317431,0.006758093,0.5333822],"study_design_scores_gemma":[0.02548611,0.004984159,0.8946688,0.0001172135,0.0001972982,0.00224695,0.000452074,0.00007475069,0.00925613,0.00302091,0.05906425,0.0004313214],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899583,0.001458288,0.0002866554,0.006723592,0.00114205,0.0000912504,0.0000222756,0.000002213522,0.0003153562],"genre_scores_gemma":[0.9939401,0.001414986,0.001340397,0.00236896,0.0008745699,0.000006634165,0.000003786933,0.00001314593,0.00003744424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5517027,"threshold_uncertainty_score":0.3635604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.028810250053983,"score_gpt":0.3986959023180364,"score_spread":0.3698856522640534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}