{"id":"W2116666774","doi":"10.1189/jlb.0908559","title":"Signaling through TLR7 enhances the immunosuppressive activity of murine CD4+CD25+ T regulatory cells","year":2009,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"TLR7; IL-2 receptor; Biology; FOXP3; T cell; Imiquimod; Interleukin 21; CD28; Cell biology; Molecular biology; Immune system; Immunology; Toll-like receptor; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000139457,0.0006303936,0.0003718859,0.0003153284,0.0001174353,0.0003350319,0.0001918988,0.0002433201,0.001203994],"category_scores_gemma":[0.0001120145,0.0001280184,0.0003017515,0.0001234029,0.0001857625,0.0001580563,0.0001960155,0.0006903214,0.0006358333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001902625,"about_ca_system_score_gemma":0.0001775607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002733328,"about_ca_topic_score_gemma":0.0005891398,"domain_scores_codex":[0.9997172,0.00005924686,0.00001867394,0.00003751163,0.00006053975,0.0001068166],"domain_scores_gemma":[0.9998825,0.00001939163,0.00002595297,0.00001249203,0.00001618393,0.00004350099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001284055,0.00004757104,0.0001411748,0.0000426053,0.000006130352,0.00005301364,0.00001013584,0.00009844625,0.9976139,0.00003355629,0.0000461019,0.001778856],"study_design_scores_gemma":[0.00005206342,0.00151133,0.003001185,0.0000133518,0.00005264564,0.0002665605,0.00004218573,0.0008496705,0.9913428,0.00005088134,0.00281095,0.00000648515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941359,0.001738712,0.000989623,0.00007143807,0.00004091634,0.00003777112,0.0001558404,0.00008351597,0.002746198],"genre_scores_gemma":[0.9949302,0.0009662363,0.001476629,0.0001086559,0.00005776341,0.00003539658,0.0003690546,0.00001848097,0.002037489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001203994,"threshold_uncertainty_score":0.004027724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159637280614692,"score_gpt":0.2593320911047349,"score_spread":0.247735718298588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}