{"id":"W2116689164","doi":"10.1530/rep-11-0008","title":"Aberrant DNA methylation at imprinted genes in testicular sperm retrieved from men with obstructive azoospermia and undergoing vasectomy reversal","year":2011,"lang":"en","type":"article","venue":"Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; B.C. Women's Hospital & Health Centre; British Columbia Centre of Excellence for Women's Health","funders":"Division of Materials Research; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Azoospermia; Andrology; Genomic imprinting; Obstructive azoospermia; DNA methylation; Methylation; Male infertility; Imprinting (psychology); Sperm; Testicular sperm extraction; Vasectomy; Biology; Spermatogenesis; Infertility; Medicine; Genetics; Gene; Population; Pregnancy; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002563712,0.0001525391,0.0001447026,0.0000384464,0.00007334594,0.00001293459,0.00005098643,0.000133392,0.00002177563],"category_scores_gemma":[0.0001837348,0.0001403065,0.00002894955,0.0001446102,0.00006594714,0.00001427635,0.00006205298,0.00007745981,0.000002679549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006632166,"about_ca_system_score_gemma":0.00004012847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003857349,"about_ca_topic_score_gemma":0.0003289093,"domain_scores_codex":[0.9987348,0.00008515654,0.0002157123,0.0006875,0.0001219714,0.0001548464],"domain_scores_gemma":[0.9993052,0.00001735454,0.0001309148,0.0003933973,0.0001019844,0.00005109787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002704886,0.00002803975,0.07858645,0.00001047591,0.00004942983,0.000003896332,0.000344356,0.00007286959,0.9159501,0.00001535464,0.000005047152,0.004663453],"study_design_scores_gemma":[0.0005295201,0.000141745,0.3128929,0.00001527454,0.00003079943,0.000007686778,0.0001049623,0.0001232907,0.6853417,0.0004287295,0.0002405098,0.0001428188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942966,0.002362858,0.002312015,0.00003909402,0.0001055632,0.0002668299,0.000005388936,0.00001686622,0.0005948328],"genre_scores_gemma":[0.9944737,0.0007291054,0.004263205,0.000005657194,0.0001998242,0.00001147817,0.0001216346,0.00002410878,0.0001712889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2343065,"threshold_uncertainty_score":0.5721533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704568392960298,"score_gpt":0.223482239905544,"score_spread":0.206436555975941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}