{"id":"W2116689164","doi":"10.1530/rep-11-0008","title":"Aberrant DNA methylation at imprinted genes in testicular sperm retrieved from men with obstructive azoospermia and undergoing vasectomy reversal","year":2011,"lang":"en","type":"article","venue":"Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; B.C. Women's Hospital & Health Centre; British Columbia Centre of Excellence for Women's Health","funders":"Division of Materials Research; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Azoospermia; Andrology; Genomic imprinting; Obstructive azoospermia; DNA methylation; Methylation; Male infertility; Imprinting (psychology); Sperm; Testicular sperm extraction; Vasectomy; Biology; Spermatogenesis; Infertility; Medicine; Genetics; Gene; Population; Pregnancy; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001234236,0.0001475996,0.0002418357,0.0007463682,0.0002132081,0.000208688,0.0001436019,0.0002034838,0.0009909666],"category_scores_gemma":[0.000514853,0.0001312241,0.000128074,0.0004973348,0.0002284758,0.00008407232,0.0001234846,0.0001462792,0.0001278132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001262324,"about_ca_system_score_gemma":0.0001163639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002068205,"about_ca_topic_score_gemma":0.002648022,"domain_scores_codex":[0.999898,0.00001850885,0.00001192673,0.00002417114,0.00002985341,0.00001761785],"domain_scores_gemma":[0.9998531,0.00003665161,0.00004423651,0.00001089095,0.00002313635,0.00003196337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006692114,0.0000408631,0.8671618,0.00009169294,0.0001578496,0.002086684,0.0008290868,0.0001220864,0.1185538,0.00004176505,0.000125529,0.0101198],"study_design_scores_gemma":[0.00001491941,0.000375605,0.9867364,0.000006324709,0.00005974877,0.004052319,0.0003162694,0.0001786575,0.0077974,0.00002173973,0.0004352547,0.00000545406],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990119,0.000562719,0.0001297236,0.00001283534,0.000004008887,0.000005601668,0.0001204078,0.000004589921,0.0001482816],"genre_scores_gemma":[0.9991768,0.0002303589,0.0001689192,0.000023569,0.000006138902,0.000003914737,0.0001885253,0.000001600328,0.0002000822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002068205,"threshold_uncertainty_score":0.004112363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704568392960298,"score_gpt":0.223482239905544,"score_spread":0.206436555975941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}